The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options
This case reports cryptococcal meningitis in an HIV positive woman on antiretroviral therapy, presenting with left middle cerebral artery stroke at 30 weeks gestation. The patient had well-controlled HIV (CD4 count over 200 cells/mL). The immunosuppressive effects of the pregnancy likely contributed...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-03-01
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| Series: | Medical Mycology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753917300520 |
| _version_ | 1828826886504972288 |
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| author | Philip D. Bright Duncan Lupiya Joep J. van Oosterhout Amy Chen Thomas S. Harrison Adrienne K. Chan |
| author_facet | Philip D. Bright Duncan Lupiya Joep J. van Oosterhout Amy Chen Thomas S. Harrison Adrienne K. Chan |
| author_sort | Philip D. Bright |
| collection | DOAJ |
| description | This case reports cryptococcal meningitis in an HIV positive woman on antiretroviral therapy, presenting with left middle cerebral artery stroke at 30 weeks gestation. The patient had well-controlled HIV (CD4 count over 200 cells/mL). The immunosuppressive effects of the pregnancy likely contributed to the development of cryptococcal disease. The patient was successfully treated with two weeks of amphotericin B followed by fluconazole, delivered a healthy baby, but remained with a permanent severe neurological deficit. |
| first_indexed | 2024-12-12T14:48:23Z |
| format | Article |
| id | doaj.art-448395f2c08646cdb1e1b368f62f4565 |
| institution | Directory Open Access Journal |
| issn | 2211-7539 |
| language | English |
| last_indexed | 2024-12-12T14:48:23Z |
| publishDate | 2018-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medical Mycology Case Reports |
| spelling | doaj.art-448395f2c08646cdb1e1b368f62f45652022-12-22T00:21:04ZengElsevierMedical Mycology Case Reports2211-75392018-03-0119C91210.1016/j.mmcr.2017.10.002The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment optionsPhilip D. Bright0Duncan Lupiya1Joep J. van Oosterhout2Amy Chen3Thomas S. Harrison4Adrienne K. Chan5Institute of Infection and Immunity, St Georges University of London, Cranmer Terrace, London SW17 0RE, United KingdomDignitas International, Zomba, MalawiDignitas International, Zomba, MalawiTrillium Health Partners, University of Toronto, CanadaInstitute of Infection and Immunity, St Georges University of London, Cranmer Terrace, London SW17 0RE, United KingdomDignitas International, Zomba, MalawiThis case reports cryptococcal meningitis in an HIV positive woman on antiretroviral therapy, presenting with left middle cerebral artery stroke at 30 weeks gestation. The patient had well-controlled HIV (CD4 count over 200 cells/mL). The immunosuppressive effects of the pregnancy likely contributed to the development of cryptococcal disease. The patient was successfully treated with two weeks of amphotericin B followed by fluconazole, delivered a healthy baby, but remained with a permanent severe neurological deficit.http://www.sciencedirect.com/science/article/pii/S2211753917300520Cryptococcal meningitisPregnancyTreatmentHIVMalawi |
| spellingShingle | Philip D. Bright Duncan Lupiya Joep J. van Oosterhout Amy Chen Thomas S. Harrison Adrienne K. Chan The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options Medical Mycology Case Reports Cryptococcal meningitis Pregnancy Treatment HIV Malawi |
| title | The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options |
| title_full | The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options |
| title_fullStr | The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options |
| title_full_unstemmed | The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options |
| title_short | The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options |
| title_sort | treatment of a pregnant hiv positive patient with cryptococcal meningitis in malawi case report and review of treatment options |
| topic | Cryptococcal meningitis Pregnancy Treatment HIV Malawi |
| url | http://www.sciencedirect.com/science/article/pii/S2211753917300520 |
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