Changes in Lipid Metabolism Enzymes in Rat Epididymal Fat after Chronic Central Leptin Infusion Are Related to Alterations in Inflammation and Insulin Signaling

Changes in Lipid Metabolism Enzymes in Rat Epididymal Fat after Chronic Central Leptin Infusion Are Related to Alterations in Inflammation and Insulin Signaling

Leptin inhibits food intake and reduces the size of body fat depots, changing adipocyte sensitivity to insulin to restrain lipid accrual. This adipokine may modulate the production of cytokines that could diminish insulin sensitivity, particularly in visceral adipose tissue. To explore this possibil...

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Bibliographic Details
Main Authors: María E. Casado, Sandra Canelles, Eduardo Arilla-Ferreiro, Laura M. Frago, Vicente Barrios
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
adipose tissue
cytokines
inflammation
insulin resistance
leptin
lipolysis
Online Access:https://www.mdpi.com/1422-0067/24/8/7065

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