Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells.

Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells.

Infection of the mammalian host by the parasitic helminth Schistosoma mansoni is accompanied by the release of excretory/secretory molecules (ES) from cercariae which aid penetration of the skin. These ES molecules are potent stimulants of innate immune cells leading to activation of acquired immuni...

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Bibliographic Details
Main Authors: Ross A Paveley, Sarah A Aynsley, Peter C Cook, Joseph D Turner, Adrian P Mountford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2759291?pdf=render

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