Comparison of The Effect of Aqueous Extracts of two Plants, Origanum Vulgare L. and Fenugreek Seeds with Anticancer Drug Cis-Platin on the Growth of Cancer Cell Lines
This study involved the effect of the aqueous extracts of two plants, Origanum vulgare L.(1), Trigonella Foenum Graecum L. (Fenugreek) seeds(2) on the growth of cancer cell lines. Rhabdomyo sarcomas (RD) of human cell line and female intestine cells of Albino mice (L20B) in vitro System. These extra...
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| Format: | Article |
| Language: | Arabic |
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College of Science for Women, University of Baghdad
2013-06-01
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| Series: | Baghdad Science Journal |
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| Online Access: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1460 |
| _version_ | 1818020373434728448 |
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| author | Baghdad Science Journal |
| author_facet | Baghdad Science Journal |
| author_sort | Baghdad Science Journal |
| collection | DOAJ |
| description | This study involved the effect of the aqueous extracts of two plants, Origanum vulgare L.(1), Trigonella Foenum Graecum L. (Fenugreek) seeds(2) on the growth of cancer cell lines. Rhabdomyo sarcomas (RD) of human cell line and female intestine cells of Albino mice (L20B) in vitro System. These extracts were compared with the known anticancer drug Cis-platinum(Cis-Pt) as a positive control. The phytochemical tests were used for screening the active compounds in plants. The inhibition activity assay was used as a parameter of the cytotoxic effect of these extracts. Cancer cell lines were treated with four concentrations of Cis-platin, 31.25, 62.5, 125 and 250 ?g/ml for 72 hour exposure time. The same concentrations were used for the other extracts. This study found that the two aqueous extracts (1,2) have a cytotoxic effects on cancer cells as could be seen from their effects on inhibition percentage and the significant differences (p |
| first_indexed | 2024-04-14T08:04:06Z |
| format | Article |
| id | doaj.art-4491a064178141f3b13cbc84d7612266 |
| institution | Directory Open Access Journal |
| issn | 2078-8665 2411-7986 |
| language | Arabic |
| last_indexed | 2024-04-14T08:04:06Z |
| publishDate | 2013-06-01 |
| publisher | College of Science for Women, University of Baghdad |
| record_format | Article |
| series | Baghdad Science Journal |
| spelling | doaj.art-4491a064178141f3b13cbc84d76122662022-12-22T02:04:48ZaraCollege of Science for Women, University of BaghdadBaghdad Science Journal2078-86652411-79862013-06-0110210.21123/bsj.10.2.368-376Comparison of The Effect of Aqueous Extracts of two Plants, Origanum Vulgare L. and Fenugreek Seeds with Anticancer Drug Cis-Platin on the Growth of Cancer Cell LinesBaghdad Science JournalThis study involved the effect of the aqueous extracts of two plants, Origanum vulgare L.(1), Trigonella Foenum Graecum L. (Fenugreek) seeds(2) on the growth of cancer cell lines. Rhabdomyo sarcomas (RD) of human cell line and female intestine cells of Albino mice (L20B) in vitro System. These extracts were compared with the known anticancer drug Cis-platinum(Cis-Pt) as a positive control. The phytochemical tests were used for screening the active compounds in plants. The inhibition activity assay was used as a parameter of the cytotoxic effect of these extracts. Cancer cell lines were treated with four concentrations of Cis-platin, 31.25, 62.5, 125 and 250 ?g/ml for 72 hour exposure time. The same concentrations were used for the other extracts. This study found that the two aqueous extracts (1,2) have a cytotoxic effects on cancer cells as could be seen from their effects on inhibition percentage and the significant differences (phttp://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1460 Fenugreek, Origanum vulgare, Cis-platin,Cancer cell lines |
| spellingShingle | Baghdad Science Journal Comparison of The Effect of Aqueous Extracts of two Plants, Origanum Vulgare L. and Fenugreek Seeds with Anticancer Drug Cis-Platin on the Growth of Cancer Cell Lines Baghdad Science Journal Fenugreek, Origanum vulgare, Cis-platin,Cancer cell lines |
| title | Comparison of The Effect of Aqueous Extracts of two Plants, Origanum Vulgare L. and Fenugreek Seeds with Anticancer Drug Cis-Platin on the Growth of Cancer Cell Lines |
| title_full | Comparison of The Effect of Aqueous Extracts of two Plants, Origanum Vulgare L. and Fenugreek Seeds with Anticancer Drug Cis-Platin on the Growth of Cancer Cell Lines |
| title_fullStr | Comparison of The Effect of Aqueous Extracts of two Plants, Origanum Vulgare L. and Fenugreek Seeds with Anticancer Drug Cis-Platin on the Growth of Cancer Cell Lines |
| title_full_unstemmed | Comparison of The Effect of Aqueous Extracts of two Plants, Origanum Vulgare L. and Fenugreek Seeds with Anticancer Drug Cis-Platin on the Growth of Cancer Cell Lines |
| title_short | Comparison of The Effect of Aqueous Extracts of two Plants, Origanum Vulgare L. and Fenugreek Seeds with Anticancer Drug Cis-Platin on the Growth of Cancer Cell Lines |
| title_sort | comparison of the effect of aqueous extracts of two plants origanum vulgare l and fenugreek seeds with anticancer drug cis platin on the growth of cancer cell lines |
| topic | Fenugreek, Origanum vulgare, Cis-platin,Cancer cell lines |
| url | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1460 |
| work_keys_str_mv | AT baghdadsciencejournal comparisonoftheeffectofaqueousextractsoftwoplantsoriganumvulgarelandfenugreekseedswithanticancerdrugcisplatinonthegrowthofcancercelllines |