Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the associated coronavirus disease 2019 (COVID-19), which severely affect the respiratory system and several organs and tissues, and may lead to death, have shown how science can respond when challenged by a global emerge...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.1052436/full |
| _version_ | 1828127203874832384 |
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| author | Agustín Valenzuela-Fernández Romina Cabrera-Rodriguez Laura Ciuffreda Silvia Perez-Yanes Judith Estevez-Herrera Rafaela González-Montelongo Julia Alcoba-Florez Rodrigo Trujillo-González Rodrigo Trujillo-González Diego García-Martínez de Artola Helena Gil-Campesino Oscar Díez-Gil José M. Lorenzo-Salazar Carlos Flores Carlos Flores Carlos Flores Carlos Flores Jonay Garcia-Luis |
| author_facet | Agustín Valenzuela-Fernández Romina Cabrera-Rodriguez Laura Ciuffreda Silvia Perez-Yanes Judith Estevez-Herrera Rafaela González-Montelongo Julia Alcoba-Florez Rodrigo Trujillo-González Rodrigo Trujillo-González Diego García-Martínez de Artola Helena Gil-Campesino Oscar Díez-Gil José M. Lorenzo-Salazar Carlos Flores Carlos Flores Carlos Flores Carlos Flores Jonay Garcia-Luis |
| author_sort | Agustín Valenzuela-Fernández |
| collection | DOAJ |
| description | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the associated coronavirus disease 2019 (COVID-19), which severely affect the respiratory system and several organs and tissues, and may lead to death, have shown how science can respond when challenged by a global emergency, offering as a response a myriad of rapid technological developments. Development of vaccines at lightning speed is one of them. SARS-CoV-2 outbreaks have stressed healthcare systems, questioning patients care by using standard non-adapted therapies and diagnostic tools. In this scenario, nanotechnology has offered new tools, techniques and opportunities for prevention, for rapid, accurate and sensitive diagnosis and treatment of COVID-19. In this review, we focus on the nanotechnological applications and nano-based materials (i.e., personal protective equipment) to combat SARS-CoV-2 transmission, infection, organ damage and for the development of new tools for virosurveillance, diagnose and immune protection by mRNA and other nano-based vaccines. All the nano-based developed tools have allowed a historical, unprecedented, real time epidemiological surveillance and diagnosis of SARS-CoV-2 infection, at community and international levels. The nano-based technology has help to predict and detect how this Sarbecovirus is mutating and the severity of the associated COVID-19 disease, thereby assisting the administration and public health services to make decisions and measures for preparedness against the emerging variants of SARS-CoV-2 and severe or lethal COVID-19. |
| first_indexed | 2024-04-11T15:46:49Z |
| format | Article |
| id | doaj.art-4495ef48f9ae48a1a31e5006c60b4e4d |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-11T15:46:49Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-4495ef48f9ae48a1a31e5006c60b4e4d2022-12-22T04:15:30ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852022-11-011010.3389/fbioe.2022.10524361052436Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19Agustín Valenzuela-Fernández0Romina Cabrera-Rodriguez1Laura Ciuffreda2Silvia Perez-Yanes3Judith Estevez-Herrera4Rafaela González-Montelongo5Julia Alcoba-Florez6Rodrigo Trujillo-González7Rodrigo Trujillo-González8Diego García-Martínez de Artola9Helena Gil-Campesino10Oscar Díez-Gil11José M. Lorenzo-Salazar12Carlos Flores13Carlos Flores14Carlos Flores15Carlos Flores16Jonay Garcia-Luis17Laboratorio de Inmunología Celular y Viral, Unidad de Farmacología, Sección de Medicina, Facultad de Ciencias de la Salud, Universidad de La Laguna, San Cristóbal de La Laguna, SpainLaboratorio de Inmunología Celular y Viral, Unidad de Farmacología, Sección de Medicina, Facultad de Ciencias de la Salud, Universidad de La Laguna, San Cristóbal de La Laguna, SpainResearch Unit, Hospital Universitario N. S. de Candelaria, Santa Cruz de Tenerife, SpainLaboratorio de Inmunología Celular y Viral, Unidad de Farmacología, Sección de Medicina, Facultad de Ciencias de la Salud, Universidad de La Laguna, San Cristóbal de La Laguna, SpainLaboratorio de Inmunología Celular y Viral, Unidad de Farmacología, Sección de Medicina, Facultad de Ciencias de la Salud, Universidad de La Laguna, San Cristóbal de La Laguna, SpainGenomics Division, Instituto Tecnológico y de Energías Renovables, Santa Cruz de Tenerife, SpainServicio de Microbiología, Hospital Universitario N. S. de Candelaria, Santa Cruz de Tenerife, SpainLaboratorio de Inmunología Celular y Viral, Unidad de Farmacología, Sección de Medicina, Facultad de Ciencias de la Salud, Universidad de La Laguna, San Cristóbal de La Laguna, SpainDepartamento de Análisis Matemático, Facultad de Ciencias, Universidad de La Laguna, Santa Cruz de Tenerife, SpainServicio de Microbiología, Hospital Universitario N. S. de Candelaria, Santa Cruz de Tenerife, SpainServicio de Microbiología, Hospital Universitario N. S. de Candelaria, Santa Cruz de Tenerife, SpainServicio de Microbiología, Hospital Universitario N. S. de Candelaria, Santa Cruz de Tenerife, SpainGenomics Division, Instituto Tecnológico y de Energías Renovables, Santa Cruz de Tenerife, SpainResearch Unit, Hospital Universitario N. S. de Candelaria, Santa Cruz de Tenerife, SpainGenomics Division, Instituto Tecnológico y de Energías Renovables, Santa Cruz de Tenerife, SpainCIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, SpainFaculty of Health Sciences, University of Fernando Pessoa Canarias, Las Palmas de Gran Canaria, SpainLaboratorio de Inmunología Celular y Viral, Unidad de Farmacología, Sección de Medicina, Facultad de Ciencias de la Salud, Universidad de La Laguna, San Cristóbal de La Laguna, SpainThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the associated coronavirus disease 2019 (COVID-19), which severely affect the respiratory system and several organs and tissues, and may lead to death, have shown how science can respond when challenged by a global emergency, offering as a response a myriad of rapid technological developments. Development of vaccines at lightning speed is one of them. SARS-CoV-2 outbreaks have stressed healthcare systems, questioning patients care by using standard non-adapted therapies and diagnostic tools. In this scenario, nanotechnology has offered new tools, techniques and opportunities for prevention, for rapid, accurate and sensitive diagnosis and treatment of COVID-19. In this review, we focus on the nanotechnological applications and nano-based materials (i.e., personal protective equipment) to combat SARS-CoV-2 transmission, infection, organ damage and for the development of new tools for virosurveillance, diagnose and immune protection by mRNA and other nano-based vaccines. All the nano-based developed tools have allowed a historical, unprecedented, real time epidemiological surveillance and diagnosis of SARS-CoV-2 infection, at community and international levels. The nano-based technology has help to predict and detect how this Sarbecovirus is mutating and the severity of the associated COVID-19 disease, thereby assisting the administration and public health services to make decisions and measures for preparedness against the emerging variants of SARS-CoV-2 and severe or lethal COVID-19.https://www.frontiersin.org/articles/10.3389/fbioe.2022.1052436/fullnanoreagentspersonal protective equipmentvaccineslipid nanoparticlesmodified mRNArecombinant proteins |
| spellingShingle | Agustín Valenzuela-Fernández Romina Cabrera-Rodriguez Laura Ciuffreda Silvia Perez-Yanes Judith Estevez-Herrera Rafaela González-Montelongo Julia Alcoba-Florez Rodrigo Trujillo-González Rodrigo Trujillo-González Diego García-Martínez de Artola Helena Gil-Campesino Oscar Díez-Gil José M. Lorenzo-Salazar Carlos Flores Carlos Flores Carlos Flores Carlos Flores Jonay Garcia-Luis Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19 Frontiers in Bioengineering and Biotechnology nanoreagents personal protective equipment vaccines lipid nanoparticles modified mRNA recombinant proteins |
| title | Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19 |
| title_full | Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19 |
| title_fullStr | Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19 |
| title_full_unstemmed | Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19 |
| title_short | Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19 |
| title_sort | nanomaterials to combat sars cov 2 strategies to prevent diagnose and treat covid 19 |
| topic | nanoreagents personal protective equipment vaccines lipid nanoparticles modified mRNA recombinant proteins |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2022.1052436/full |
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