The study of leptin concentration in saliva during orthodontic treatment, periodontal diseases and wound healing in the oral mucosa-review

Background The oral cavity is a very complex environment characterized by numerous interactions between different tissues, secretions from various glands, foods, air and microorganisms. Leptin is a hormone-like protein, which plays an important role in protection of host against inflammation and in...

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Main Authors: Izabela Cwalina, Marta Komarowska, Ewelina Dargiewicz, Adam Hermanowicz
Format: Article
Language:English
Published: Kazimierz Wielki University 2018-12-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6433
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author Izabela Cwalina
Marta Komarowska
Ewelina Dargiewicz
Adam Hermanowicz
author_facet Izabela Cwalina
Marta Komarowska
Ewelina Dargiewicz
Adam Hermanowicz
author_sort Izabela Cwalina
collection DOAJ
description Background The oral cavity is a very complex environment characterized by numerous interactions between different tissues, secretions from various glands, foods, air and microorganisms. Leptin is a hormone-like protein, which plays an important role in protection of host against inflammation and infection. It exhibits many physiological properties. Some studies have reported changes in leptin levels during orthodontic treatment, wound healing, periodontal disease. The aim of the paper was to review the salivary leptin role in each of these cases. Methods Articles published before November 2018 were obtained from PubMed, Dentistry & Oral Sciences Source. Inclusion criteria were: a) empirically based b) peer-reviewed. Discussion and results Salivary leptin levels significantly decrease during orthodontic tooth movement and periodontal diseases. However, it increases while wound healing in the oral mucosa. Conclusion There is a correlation between tooth movement and leptin level. Obese patients could have lesser tooth movement. This hormone promotes wound healing and angiogenesis in oral cavity. Leptin concentration in saliva increases in patients with periodontitis.
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spelling doaj.art-449c8437121f4ced8309ccc7799733e62022-12-21T19:11:56ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062018-12-0181274375010.5281/zenodo.25291725781The study of leptin concentration in saliva during orthodontic treatment, periodontal diseases and wound healing in the oral mucosa-reviewIzabela Cwalina0Marta Komarowska1Ewelina Dargiewicz2Adam Hermanowicz3Ortho-Dent Private Dental Practice, BialystokPediatric Surgery Department; Medical University of Bialystok; BialystokDepartment of Orthodontics; Medical University of Bialystok; BialystokPediatric Surgery Department; Medical University of Bialystok; BialystokBackground The oral cavity is a very complex environment characterized by numerous interactions between different tissues, secretions from various glands, foods, air and microorganisms. Leptin is a hormone-like protein, which plays an important role in protection of host against inflammation and infection. It exhibits many physiological properties. Some studies have reported changes in leptin levels during orthodontic treatment, wound healing, periodontal disease. The aim of the paper was to review the salivary leptin role in each of these cases. Methods Articles published before November 2018 were obtained from PubMed, Dentistry & Oral Sciences Source. Inclusion criteria were: a) empirically based b) peer-reviewed. Discussion and results Salivary leptin levels significantly decrease during orthodontic tooth movement and periodontal diseases. However, it increases while wound healing in the oral mucosa. Conclusion There is a correlation between tooth movement and leptin level. Obese patients could have lesser tooth movement. This hormone promotes wound healing and angiogenesis in oral cavity. Leptin concentration in saliva increases in patients with periodontitis.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6433salivaleptinhealingorthodontic tooth movementperiodontitis
spellingShingle Izabela Cwalina
Marta Komarowska
Ewelina Dargiewicz
Adam Hermanowicz
The study of leptin concentration in saliva during orthodontic treatment, periodontal diseases and wound healing in the oral mucosa-review
Journal of Education, Health and Sport
saliva
leptin
healing
orthodontic tooth movement
periodontitis
title The study of leptin concentration in saliva during orthodontic treatment, periodontal diseases and wound healing in the oral mucosa-review
title_full The study of leptin concentration in saliva during orthodontic treatment, periodontal diseases and wound healing in the oral mucosa-review
title_fullStr The study of leptin concentration in saliva during orthodontic treatment, periodontal diseases and wound healing in the oral mucosa-review
title_full_unstemmed The study of leptin concentration in saliva during orthodontic treatment, periodontal diseases and wound healing in the oral mucosa-review
title_short The study of leptin concentration in saliva during orthodontic treatment, periodontal diseases and wound healing in the oral mucosa-review
title_sort study of leptin concentration in saliva during orthodontic treatment periodontal diseases and wound healing in the oral mucosa review
topic saliva
leptin
healing
orthodontic tooth movement
periodontitis
url http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6433
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