Humans and Mice Display Opposing Patterns of “Browning” Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots

Humans and Mice Display Opposing Patterns of “Browning” Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots

Visceral adiposity is much more strongly associated with cardiometabolic disease in humans than subcutaneous adiposity. Browning, the appearance of brown-like adipocytes in the white adipose tissue (WAT), has been shown to protect mice against metabolic dysfunction, suggesting the possibility of new...

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Bibliographic Details
Main Authors: Maria A. Zuriaga, Jose J. Fuster, Noyan Gokce, Kenneth Walsh
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
browning
adipose tissue
gene expression
mouse
human
Online Access:http://journal.frontiersin.org/article/10.3389/fcvm.2017.00027/full

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