Main Renal Artery Plus Branch Ablation in the Treatment of Resistant Hypertension with Renal Denervation
<p class="first" id="d611006e189"> <b>Objective:</b> To study the safety and efficacy of denervation of renal artery branches in the treatment of resistant hypertension. </p><p id="d611006e194">...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2021-11-01
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| Series: | Cardiovascular Innovations and Applications |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2021.0024 |
| _version_ | 1797793573423284224 |
|---|---|
| author | Tian-Jiao Lyu Ling-Yan Li Xu Wang Jian Ye Jun-Qing Gao Zong-Jun Liu |
| author_facet | Tian-Jiao Lyu Ling-Yan Li Xu Wang Jian Ye Jun-Qing Gao Zong-Jun Liu |
| author_sort | Tian-Jiao Lyu |
| collection | DOAJ |
| description | <p class="first" id="d611006e189">
<b>Objective:</b> To study the safety and efficacy of denervation of renal artery branches in the treatment
of resistant hypertension.
</p><p id="d611006e194">
<b>Methods:</b> Sixty patients with resistant hypertension were enrolled. The patients were randomly
assigned to the main renal artery plus branch ablation group or the main renal artery
ablation group. The clinical data and operation-related parameters, including number
of ablation points, temperature, and average energy, were recorded. Ambulatory blood
pressure was taken for all patients at the baseline and at 6 months after treatment.
Office blood pressure was recorded before treatment and after treatment every 3 months
for 2 years.
</p><p id="d611006e199">
<b>Results:</b> Sixty patients with resistant hypertension were enrolled in this study. There were
30 patients in each group. Angiography was performed after ablation. No renal artery
complications, such as stenosis and dissection, occurred in the two groups. There
was no significant difference in age, sex, BMI, comorbid disease, and medication between
the two groups (P>0.05). The number of ablation points for the main renal artery plus
branch ablation group was greater than that for the main renal artery ablation group.
The office blood pressure and 24-hour blood pressure were significantly lower 6 months
after treatment than before treatment in both groups (P<0.05). Office blood pressure
in the main renal artery plus branch ablation group was lower than that in the main
renal artery ablation group during the 3–12-month follow-up period, with a statistical
difference. However, as the follow-up time increased, the difference disappeared.
</p><p id="d611006e204">
<b>Conclusion:</b> The results of this study show that main renal artery plus branch ablation is a safe
interventional method, but there was no obvious advantage on long-term follow-up compared
with only main renal artery ablation.
</p> |
| first_indexed | 2024-03-13T02:49:16Z |
| format | Article |
| id | doaj.art-44a4c0a5d4e647d69c17569a1313d1e4 |
| institution | Directory Open Access Journal |
| issn | 2009-8618 2009-8782 |
| language | English |
| last_indexed | 2024-03-13T02:49:16Z |
| publishDate | 2021-11-01 |
| publisher | Compuscript Ltd |
| record_format | Article |
| series | Cardiovascular Innovations and Applications |
| spelling | doaj.art-44a4c0a5d4e647d69c17569a1313d1e42023-06-28T13:57:14ZengCompuscript LtdCardiovascular Innovations and Applications2009-86182009-87822021-11-01629110.15212/CVIA.2021.0024Main Renal Artery Plus Branch Ablation in the Treatment of Resistant Hypertension with Renal DenervationTian-Jiao LyuLing-Yan LiXu WangJian YeJun-Qing GaoZong-Jun Liu<p class="first" id="d611006e189"> <b>Objective:</b> To study the safety and efficacy of denervation of renal artery branches in the treatment of resistant hypertension. </p><p id="d611006e194"> <b>Methods:</b> Sixty patients with resistant hypertension were enrolled. The patients were randomly assigned to the main renal artery plus branch ablation group or the main renal artery ablation group. The clinical data and operation-related parameters, including number of ablation points, temperature, and average energy, were recorded. Ambulatory blood pressure was taken for all patients at the baseline and at 6 months after treatment. Office blood pressure was recorded before treatment and after treatment every 3 months for 2 years. </p><p id="d611006e199"> <b>Results:</b> Sixty patients with resistant hypertension were enrolled in this study. There were 30 patients in each group. Angiography was performed after ablation. No renal artery complications, such as stenosis and dissection, occurred in the two groups. There was no significant difference in age, sex, BMI, comorbid disease, and medication between the two groups (P>0.05). The number of ablation points for the main renal artery plus branch ablation group was greater than that for the main renal artery ablation group. The office blood pressure and 24-hour blood pressure were significantly lower 6 months after treatment than before treatment in both groups (P<0.05). Office blood pressure in the main renal artery plus branch ablation group was lower than that in the main renal artery ablation group during the 3–12-month follow-up period, with a statistical difference. However, as the follow-up time increased, the difference disappeared. </p><p id="d611006e204"> <b>Conclusion:</b> The results of this study show that main renal artery plus branch ablation is a safe interventional method, but there was no obvious advantage on long-term follow-up compared with only main renal artery ablation. </p>https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2021.0024 |
| spellingShingle | Tian-Jiao Lyu Ling-Yan Li Xu Wang Jian Ye Jun-Qing Gao Zong-Jun Liu Main Renal Artery Plus Branch Ablation in the Treatment of Resistant Hypertension with Renal Denervation Cardiovascular Innovations and Applications |
| title | Main Renal Artery Plus Branch Ablation in the Treatment of Resistant Hypertension with Renal Denervation |
| title_full | Main Renal Artery Plus Branch Ablation in the Treatment of Resistant Hypertension with Renal Denervation |
| title_fullStr | Main Renal Artery Plus Branch Ablation in the Treatment of Resistant Hypertension with Renal Denervation |
| title_full_unstemmed | Main Renal Artery Plus Branch Ablation in the Treatment of Resistant Hypertension with Renal Denervation |
| title_short | Main Renal Artery Plus Branch Ablation in the Treatment of Resistant Hypertension with Renal Denervation |
| title_sort | main renal artery plus branch ablation in the treatment of resistant hypertension with renal denervation |
| url | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2021.0024 |
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