Phosphatase complex Pph3/Psy2 is involved in regulation of efficient non-homologous end-joining pathway in the yeast Saccharomyces cerevisiae.

Phosphatase complex Pph3/Psy2 is involved in regulation of efficient non-homologous end-joining pathway in the yeast Saccharomyces cerevisiae.

One of the main mechanisms for double stranded DNA break (DSB) repair is through the non-homologous end-joining (NHEJ) pathway. Using plasmid and chromosomal repair assays, we showed that deletion mutant strains for interacting proteins Pph3p and Psy2p had reduced efficiencies in NHEJ. We further ob...

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Bibliographic Details
Main Authors: Katayoun Omidi, Mohsen Hooshyar, Matthew Jessulat, Bahram Samanfar, Megan Sanders, Daniel Burnside, Sylvain Pitre, Andrew Schoenrock, Jianhua Xu, Mohan Babu, Ashkan Golshani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3909046?pdf=render

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