Phanerosides A–X, Phenylpropanoid Esters of Sucrose from the Rattans of <i>Phanera championii</i> Benth

Twenty-four new phenylpropanoid esters of sucrose, phanerosides A–X (<b>1</b>–<b>24</b>), were isolated from an EtOH extract of the rattans of <i>Phanera championii</i> Benth. (Fabaceae). Their structures were elucidated on the basis of comprehensive spectroscopic...

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Bibliographic Details
Main Authors: Ya-Jie Hu, Qian Lan, Bao-Jun Su, Dong Liang
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/12/4767
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Summary:Twenty-four new phenylpropanoid esters of sucrose, phanerosides A–X (<b>1</b>–<b>24</b>), were isolated from an EtOH extract of the rattans of <i>Phanera championii</i> Benth. (Fabaceae). Their structures were elucidated on the basis of comprehensive spectroscopic data analysis. A wide range of structural analogues were presented due to the different numbers and positions of acetyl substituents and the structures of phenylpropanoid moieties. Phenylpropanoid esters of sucrose were isolated from the Fabaceae family for the first time. Biologically, the inhibitory effects of compounds <b>6</b> and <b>21</b> on NO production in LPS-induced BV-2 microglial cells were better than that of the positive control, with IC<sub>50</sub> values of 6.7 and 5.2 μM, respectively. The antioxidant activity assay showed that compounds <b>5</b>, <b>15</b>, <b>17</b>, and <b>24</b> displayed moderate DPPH radical scavenging activity, with IC<sub>50</sub> values ranging from 34.9 to 43.9 μM.
ISSN:1420-3049