Osteoporosis and Alveolar Bone Health in Periodontitis Niche: A Predisposing Factors-Centered Review
Periodontitis is a periodontal inflammatory condition that results from disrupted periodontal host–microbe homeostasis, manifested by the destruction of tooth-supporting structures, especially inflammatory alveolar bone loss. Osteoporosis is characterized by systemic deterioration of bone mass and m...
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MDPI AG
2022-10-01
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| Online Access: | https://www.mdpi.com/2073-4409/11/21/3380 |
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| author | Li Zhu Chenchen Zhou Shuo Chen Danyuan Huang Yukun Jiang Yuanchen Lan Shujuan Zou Yuyu Li |
| author_facet | Li Zhu Chenchen Zhou Shuo Chen Danyuan Huang Yukun Jiang Yuanchen Lan Shujuan Zou Yuyu Li |
| author_sort | Li Zhu |
| collection | DOAJ |
| description | Periodontitis is a periodontal inflammatory condition that results from disrupted periodontal host–microbe homeostasis, manifested by the destruction of tooth-supporting structures, especially inflammatory alveolar bone loss. Osteoporosis is characterized by systemic deterioration of bone mass and microarchitecture. The roles of many systemic factors have been identified in the pathogenesis of osteoporosis, including endocrine change, metabolic disorders, health-impaired behaviors and mental stress. The prevalence rate of osteoporotic fracture is in sustained elevation in the past decades. Recent studies suggest that individuals with concomitant osteoporosis are more vulnerable to periodontal impairment. Current reviews of worse periodontal status in the context of osteoporosis are limited, mainly centering on the impacts of menopausal and diabetic osteoporosis on periodontitis. Herein, this review article makes an effort to provide a comprehensive view of the relationship between osteoporosis and periodontitis, with a focus on clarifying how those risk factors in osteoporotic populations modify the alveolar bone homeostasis in the periodontitis niche. |
| first_indexed | 2024-03-09T19:11:14Z |
| format | Article |
| id | doaj.art-44acc4de24a74406b6dd9097b1f38b1e |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-09T19:11:14Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-44acc4de24a74406b6dd9097b1f38b1e2023-11-24T04:07:45ZengMDPI AGCells2073-44092022-10-011121338010.3390/cells11213380Osteoporosis and Alveolar Bone Health in Periodontitis Niche: A Predisposing Factors-Centered ReviewLi Zhu0Chenchen Zhou1Shuo Chen2Danyuan Huang3Yukun Jiang4Yuanchen Lan5Shujuan Zou6Yuyu Li7State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaPeriodontitis is a periodontal inflammatory condition that results from disrupted periodontal host–microbe homeostasis, manifested by the destruction of tooth-supporting structures, especially inflammatory alveolar bone loss. Osteoporosis is characterized by systemic deterioration of bone mass and microarchitecture. The roles of many systemic factors have been identified in the pathogenesis of osteoporosis, including endocrine change, metabolic disorders, health-impaired behaviors and mental stress. The prevalence rate of osteoporotic fracture is in sustained elevation in the past decades. Recent studies suggest that individuals with concomitant osteoporosis are more vulnerable to periodontal impairment. Current reviews of worse periodontal status in the context of osteoporosis are limited, mainly centering on the impacts of menopausal and diabetic osteoporosis on periodontitis. Herein, this review article makes an effort to provide a comprehensive view of the relationship between osteoporosis and periodontitis, with a focus on clarifying how those risk factors in osteoporotic populations modify the alveolar bone homeostasis in the periodontitis niche.https://www.mdpi.com/2073-4409/11/21/3380periodontitisosteoporosishormonesmetabolic disorderslifestylepsychological stress |
| spellingShingle | Li Zhu Chenchen Zhou Shuo Chen Danyuan Huang Yukun Jiang Yuanchen Lan Shujuan Zou Yuyu Li Osteoporosis and Alveolar Bone Health in Periodontitis Niche: A Predisposing Factors-Centered Review Cells periodontitis osteoporosis hormones metabolic disorders lifestyle psychological stress |
| title | Osteoporosis and Alveolar Bone Health in Periodontitis Niche: A Predisposing Factors-Centered Review |
| title_full | Osteoporosis and Alveolar Bone Health in Periodontitis Niche: A Predisposing Factors-Centered Review |
| title_fullStr | Osteoporosis and Alveolar Bone Health in Periodontitis Niche: A Predisposing Factors-Centered Review |
| title_full_unstemmed | Osteoporosis and Alveolar Bone Health in Periodontitis Niche: A Predisposing Factors-Centered Review |
| title_short | Osteoporosis and Alveolar Bone Health in Periodontitis Niche: A Predisposing Factors-Centered Review |
| title_sort | osteoporosis and alveolar bone health in periodontitis niche a predisposing factors centered review |
| topic | periodontitis osteoporosis hormones metabolic disorders lifestyle psychological stress |
| url | https://www.mdpi.com/2073-4409/11/21/3380 |
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