Collagen X Is Dispensable for Hypertrophic Differentiation and Endochondral Ossification of Human iPSC‐Derived Chondrocytes

Collagen X Is Dispensable for Hypertrophic Differentiation and Endochondral Ossification of Human iPSC‐Derived Chondrocytes

ABSTRACT Collagen X is a non‐fibril collagen produced by hypertrophic chondrocytes and was believed to associate with the calcification process of growth plate cartilage. The homozygous loss of Col10a1 gene in mice, however, demonstrated no remarkable effects on growth plate formation or skeletal de...

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Bibliographic Details
Main Authors: Takeshi Kamakura, Yonghui Jin, Megumi Nishio, Sanae Nagata, Masayuki Fukuda, Liping Sun, Shunsuke Kawai, Junya Toguchida
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:JBMR Plus
Subjects:
GROWTH PLATE
CHONDROCYTE AND CARTILAGE BIOLOGY
DISEASES AND DISORDERS OF/RELATED TO BONE
COLLAGEN
BONE MATRIX
Online Access:https://doi.org/10.1002/jbm4.10737

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