Preventing the onset of depressive disorders in low-and middle-income countries: An overview

Depressive disorders constitute an important and costly public health problem and worldwide most of the disease burden is suffered in low-and middle-income countries (LMICs). Treatments only have limited possibilities to reduce the disease burden of depressive disorders. Prevention may be one of the...

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Main Author: Pim Cuijpers
Format: Article
Language:English
Published: Cambridge University Press 2023-01-01
Series:Cambridge Prisms: Global Mental Health
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2054425123000225/type/journal_article
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author Pim Cuijpers
author_facet Pim Cuijpers
author_sort Pim Cuijpers
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description Depressive disorders constitute an important and costly public health problem and worldwide most of the disease burden is suffered in low-and middle-income countries (LMICs). Treatments only have limited possibilities to reduce the disease burden of depressive disorders. Prevention may be one of the alternative ways to further reduce the disease burden of depressive disorders. In this paper, the results of a subgroup analysis of a previous meta-analysis on the effect of preventive interventions on the incidence of depressive disorders was undertaken. Only 6% of all trials examining the possibility to prevent the onset of major depression have been conducted in LMICs, and these studies find significantly smaller effects than those in high-income settings. It is too early, therefore, to consider implementing and disseminating preventive interventions in LMICS. However, in optimal conditions and assuming that evidence-based preventive interventions will be developed, investments should be made into treatment, universal, selective and indicated prevention, as well as in social institutions focusing on larger risk factors for mental health problems.
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spelling doaj.art-44b69041a4104fcba6b000fc7dc7f4ed2023-06-02T05:23:55ZengCambridge University PressCambridge Prisms: Global Mental Health2054-42512023-01-011010.1017/gmh.2023.22Preventing the onset of depressive disorders in low-and middle-income countries: An overviewPim Cuijpers0https://orcid.org/0000-0001-5497-2743Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands and International Institute for Psychotherapy, Babeș-Bolyai University, Cluj-Napoca, RomaniaDepressive disorders constitute an important and costly public health problem and worldwide most of the disease burden is suffered in low-and middle-income countries (LMICs). Treatments only have limited possibilities to reduce the disease burden of depressive disorders. Prevention may be one of the alternative ways to further reduce the disease burden of depressive disorders. In this paper, the results of a subgroup analysis of a previous meta-analysis on the effect of preventive interventions on the incidence of depressive disorders was undertaken. Only 6% of all trials examining the possibility to prevent the onset of major depression have been conducted in LMICs, and these studies find significantly smaller effects than those in high-income settings. It is too early, therefore, to consider implementing and disseminating preventive interventions in LMICS. However, in optimal conditions and assuming that evidence-based preventive interventions will be developed, investments should be made into treatment, universal, selective and indicated prevention, as well as in social institutions focusing on larger risk factors for mental health problems.https://www.cambridge.org/core/product/identifier/S2054425123000225/type/journal_articledepressionmajor depressive disorderpreventionlow- and middle income countriesrandomized controlled trialsmeta-analysisuniversal preventionselective preventionindicated prevention
spellingShingle Pim Cuijpers
Preventing the onset of depressive disorders in low-and middle-income countries: An overview
Cambridge Prisms: Global Mental Health
depression
major depressive disorder
prevention
low- and middle income countries
randomized controlled trials
meta-analysis
universal prevention
selective prevention
indicated prevention
title Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title_full Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title_fullStr Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title_full_unstemmed Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title_short Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title_sort preventing the onset of depressive disorders in low and middle income countries an overview
topic depression
major depressive disorder
prevention
low- and middle income countries
randomized controlled trials
meta-analysis
universal prevention
selective prevention
indicated prevention
url https://www.cambridge.org/core/product/identifier/S2054425123000225/type/journal_article
work_keys_str_mv AT pimcuijpers preventingtheonsetofdepressivedisordersinlowandmiddleincomecountriesanoverview