Benefits of Wine Polyphenols on Human Health: A Review
<p>This paper presents an overview of the health benefits of wine polyphenols, induced by a moderate consumption. Several studies have shown that moderate wine intake may have many beneficial effects on human health and these effects are mainly attributed to the phenolic derivatives, especial...
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| Format: | Article |
| Language: | English |
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AcademicPres
2014-11-01
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| Series: | Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology |
| Subjects: | |
| Online Access: | http://journals.usamvcluj.ro/index.php/fst/article/view/10860 |
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| author | Roxana Banc Carmen Socaciu Doina Miere Lorena Filip Anamaria Cozma Oana Stanciu Felicia Loghin |
| author_facet | Roxana Banc Carmen Socaciu Doina Miere Lorena Filip Anamaria Cozma Oana Stanciu Felicia Loghin |
| author_sort | Roxana Banc |
| collection | DOAJ |
| description | <p>This paper presents an overview of the health benefits of wine polyphenols, induced by a moderate consumption. Several studies have shown that moderate wine intake may have many beneficial effects on human health and these effects are mainly attributed to the phenolic derivatives, especially flavonoids. Beside flavonoid compounds, phenolic acids (hydroxybenzoic acids and hydroxycinnamic acids) and stilbenes are important non-flavonoid compounds present in grapes and wine. In the present review, the biological role of these classes of polyphenols in wine is briefly introduced, together with the knowledge on their bioavailability. The health-protective properties of wines are mainly due to antioxidant activities and capability to eliminate free radicals of the phenolic compounds. Additionally, these compounds (e.g. catechin and their oligomers and proanthocyanidins, quercetin, resveratrol) have been reported to have multiple biological activities, including cardioprotective, anti-carcinogenic, anti-atherogenic, anti-inflammatory, antiviral and antibacterial properties. Epidemiological and clinical studies have pointed out that regular and moderate red wine consumption (one to two glasses a day) is associated with decreased incidence of cardiovascular disease, hypertension, diabetes, and certain types of cancer, including lung, esophagus, stomach, colon, endometrium, ovarian and prostate cancer. The bioavailability of phenolic compounds differs largely among different polyphenol molecules, thus the most abundant polyphenols in wines are not necessarily those leading to the highest levels of active metabolites in target tissues. Therefore, since wine is a complex mixture, it is likely that a multitude of chemical constituents, as well as their metabolites, act synergistically on human health.</p> |
| first_indexed | 2024-12-22T08:27:24Z |
| format | Article |
| id | doaj.art-44b788e20b9f47a0bc711d38457e503d |
| institution | Directory Open Access Journal |
| issn | 2344-2344 2344-5300 |
| language | English |
| last_indexed | 2024-12-22T08:27:24Z |
| publishDate | 2014-11-01 |
| publisher | AcademicPres |
| record_format | Article |
| series | Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology |
| spelling | doaj.art-44b788e20b9f47a0bc711d38457e503d2022-12-21T18:32:36ZengAcademicPresBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology2344-23442344-53002014-11-01712798710.15835/buasvmcn-fst:108608821Benefits of Wine Polyphenols on Human Health: A ReviewRoxana Banc0Carmen Socaciu1Doina Miere2Lorena Filip3Anamaria Cozma4Oana Stanciu5Felicia Loghin6University of Medicine and Pharmacy “Iuliu Haţieganu”, Faculty of Pharmacy, Department of Bromatology, Hygiene, Nutrition, 6 Pasteur Street, 400349 Cluj-NapocaUniversity of Agricultural Science and Veterinary Medicine, Faculty of Food Science and Technology, 3-5 Manastur Street, 400372 Cluj-NapocaUniversity of Medicine and Pharmacy “Iuliu Haţieganu”, Faculty of Pharmacy, Department of Bromatology, Hygiene, Nutrition, 6 Pasteur Street, 400349 Cluj-NapocaUniversity of Medicine and Pharmacy “Iuliu Haţieganu”, Faculty of Pharmacy, Department of Bromatology, Hygiene, Nutrition, 6 Pasteur Street, 400349 Cluj-NapocaUniversity of Medicine and Pharmacy “Iuliu Haţieganu”, Faculty of Pharmacy, Department of Bromatology, Hygiene, Nutrition, 6 Pasteur Street, 400349 Cluj-NapocaUniversity of Medicine and Pharmacy “Iuliu Haţieganu”, Faculty of Pharmacy, Department of Bromatology, Hygiene, Nutrition, 6 Pasteur Street, 400349 Cluj-NapocaUniversity of Medicine and Pharmacy “Iuliu Hatieganu”, Faculty of Pharmacy, Department of Toxicology, 6 Pasteur Street, 400349 Cluj-Napoca<p>This paper presents an overview of the health benefits of wine polyphenols, induced by a moderate consumption. Several studies have shown that moderate wine intake may have many beneficial effects on human health and these effects are mainly attributed to the phenolic derivatives, especially flavonoids. Beside flavonoid compounds, phenolic acids (hydroxybenzoic acids and hydroxycinnamic acids) and stilbenes are important non-flavonoid compounds present in grapes and wine. In the present review, the biological role of these classes of polyphenols in wine is briefly introduced, together with the knowledge on their bioavailability. The health-protective properties of wines are mainly due to antioxidant activities and capability to eliminate free radicals of the phenolic compounds. Additionally, these compounds (e.g. catechin and their oligomers and proanthocyanidins, quercetin, resveratrol) have been reported to have multiple biological activities, including cardioprotective, anti-carcinogenic, anti-atherogenic, anti-inflammatory, antiviral and antibacterial properties. Epidemiological and clinical studies have pointed out that regular and moderate red wine consumption (one to two glasses a day) is associated with decreased incidence of cardiovascular disease, hypertension, diabetes, and certain types of cancer, including lung, esophagus, stomach, colon, endometrium, ovarian and prostate cancer. The bioavailability of phenolic compounds differs largely among different polyphenol molecules, thus the most abundant polyphenols in wines are not necessarily those leading to the highest levels of active metabolites in target tissues. Therefore, since wine is a complex mixture, it is likely that a multitude of chemical constituents, as well as their metabolites, act synergistically on human health.</p>http://journals.usamvcluj.ro/index.php/fst/article/view/10860anthocyanins, flavonoids, moderate wine consumption, procyanidins, stilbenes |
| spellingShingle | Roxana Banc Carmen Socaciu Doina Miere Lorena Filip Anamaria Cozma Oana Stanciu Felicia Loghin Benefits of Wine Polyphenols on Human Health: A Review Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology anthocyanins, flavonoids, moderate wine consumption, procyanidins, stilbenes |
| title | Benefits of Wine Polyphenols on Human Health: A Review |
| title_full | Benefits of Wine Polyphenols on Human Health: A Review |
| title_fullStr | Benefits of Wine Polyphenols on Human Health: A Review |
| title_full_unstemmed | Benefits of Wine Polyphenols on Human Health: A Review |
| title_short | Benefits of Wine Polyphenols on Human Health: A Review |
| title_sort | benefits of wine polyphenols on human health a review |
| topic | anthocyanins, flavonoids, moderate wine consumption, procyanidins, stilbenes |
| url | http://journals.usamvcluj.ro/index.php/fst/article/view/10860 |
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