New Insight on Insulinoma Treatment in a Pet Rat—A Case Report
Insulinomas are insulin-producing tumors of pancreatic beta cells that cause hypoglycemia. They are extremely common in ferrets but have also been reported in guinea pigs and rats. This is a case report of an older rat with spontaneous insulinoma, which was confirmed by histopathology. The patient w...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/20/2783 |
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| author | Agata Godlewska Karolina Barszcz Aleksandra Orzechowska Aleksandra Małek-Sanigórska |
| author_facet | Agata Godlewska Karolina Barszcz Aleksandra Orzechowska Aleksandra Małek-Sanigórska |
| author_sort | Agata Godlewska |
| collection | DOAJ |
| description | Insulinomas are insulin-producing tumors of pancreatic beta cells that cause hypoglycemia. They are extremely common in ferrets but have also been reported in guinea pigs and rats. This is a case report of an older rat with spontaneous insulinoma, which was confirmed by histopathology. The patient was presented at a regular check-up due to a chronic respiratory disease. The owner noticed progressive weakness of the hind limbs, which is quite commonly seen in older rats. A blood exam revealed hypoglycemia, which could have been associated with paraparesis. The patient responded to treatment with oral dexamethasone and was regularly monitored. It survived nearly 4 months in good general condition. The rat finally died most probably due to severe hypoglycemia caused by progression of the pancreatic tumor. This is the first report of a pet rat with insulinoma that was successfully treated with glucocorticoids. |
| first_indexed | 2024-03-09T20:51:25Z |
| format | Article |
| id | doaj.art-44b9b163c5d04405a00f6ca2192b66dd |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T20:51:25Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-44b9b163c5d04405a00f6ca2192b66dd2023-11-23T22:31:49ZengMDPI AGAnimals2076-26152022-10-011220278310.3390/ani12202783New Insight on Insulinoma Treatment in a Pet Rat—A Case ReportAgata Godlewska0Karolina Barszcz1Aleksandra Orzechowska2Aleksandra Małek-Sanigórska3Department of Morphological Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences SGGW, 02-787 Warsaw, PolandDepartment of Morphological Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences SGGW, 02-787 Warsaw, PolandEDINA Veterinary Clinic PulsVet in Warsaw, 02-801 Warsaw, PolandEDINA Veterinary Clinic PulsVet in Warsaw, 02-801 Warsaw, PolandInsulinomas are insulin-producing tumors of pancreatic beta cells that cause hypoglycemia. They are extremely common in ferrets but have also been reported in guinea pigs and rats. This is a case report of an older rat with spontaneous insulinoma, which was confirmed by histopathology. The patient was presented at a regular check-up due to a chronic respiratory disease. The owner noticed progressive weakness of the hind limbs, which is quite commonly seen in older rats. A blood exam revealed hypoglycemia, which could have been associated with paraparesis. The patient responded to treatment with oral dexamethasone and was regularly monitored. It survived nearly 4 months in good general condition. The rat finally died most probably due to severe hypoglycemia caused by progression of the pancreatic tumor. This is the first report of a pet rat with insulinoma that was successfully treated with glucocorticoids.https://www.mdpi.com/2076-2615/12/20/2783insulinomapancreatic tumorpancreatic islet cell adenomahypoglycemiaparaparesisposterior weakness |
| spellingShingle | Agata Godlewska Karolina Barszcz Aleksandra Orzechowska Aleksandra Małek-Sanigórska New Insight on Insulinoma Treatment in a Pet Rat—A Case Report Animals insulinoma pancreatic tumor pancreatic islet cell adenoma hypoglycemia paraparesis posterior weakness |
| title | New Insight on Insulinoma Treatment in a Pet Rat—A Case Report |
| title_full | New Insight on Insulinoma Treatment in a Pet Rat—A Case Report |
| title_fullStr | New Insight on Insulinoma Treatment in a Pet Rat—A Case Report |
| title_full_unstemmed | New Insight on Insulinoma Treatment in a Pet Rat—A Case Report |
| title_short | New Insight on Insulinoma Treatment in a Pet Rat—A Case Report |
| title_sort | new insight on insulinoma treatment in a pet rat a case report |
| topic | insulinoma pancreatic tumor pancreatic islet cell adenoma hypoglycemia paraparesis posterior weakness |
| url | https://www.mdpi.com/2076-2615/12/20/2783 |
| work_keys_str_mv | AT agatagodlewska newinsightoninsulinomatreatmentinapetratacasereport AT karolinabarszcz newinsightoninsulinomatreatmentinapetratacasereport AT aleksandraorzechowska newinsightoninsulinomatreatmentinapetratacasereport AT aleksandramałeksanigorska newinsightoninsulinomatreatmentinapetratacasereport |