Can the current monkeypox affect the heart? A systematic review of case series and case report
Abstract Background Monkeypox is a zoonotic viral infection first reported in May 2022. Monkeypox cases present with prodromal symptoms, rash, and/or systemic complications. This study systematically reviews the monkeypox cases presented with any cardiac complications. Methods A systematic literatur...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-023-03351-3 |
| _version_ | 1797789952969277440 |
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| author | Reem Sayad Abdelmonem Siddiq Ahmed Hashim Ahmed Saad Elsaeidy |
| author_facet | Reem Sayad Abdelmonem Siddiq Ahmed Hashim Ahmed Saad Elsaeidy |
| author_sort | Reem Sayad |
| collection | DOAJ |
| description | Abstract Background Monkeypox is a zoonotic viral infection first reported in May 2022. Monkeypox cases present with prodromal symptoms, rash, and/or systemic complications. This study systematically reviews the monkeypox cases presented with any cardiac complications. Methods A systematic literature search was done to locate papers that discuss any cardiac complications associated with monkeypox; then, data were analyzed qualitatively. Results Nine articles, including the 13 cases that reported cardiac complications of the disease, were included in the review. Five cases previously had sex with men, and two cases had unprotected intercourse, which reveals the importance of the sexual route in disease transmission. All cases have a wide spectrum of cardiac complications, such as acute myocarditis, pericarditis, pericardial effusion, and myopericarditis. Conclusion This study clarifies the potential for cardiac complications in monkeypox cases and provides avenues for future research to determine the underlying mechanism. Also, we found that the cases with pericarditis were treated with colchicine, and those with myocarditis were treated with supportive care or cardioprotective treatment (Bisoprolol and Ramipril). Furthermore, Tecovirimat is used as an antiviral drug for 14 days. |
| first_indexed | 2024-03-13T01:57:18Z |
| format | Article |
| id | doaj.art-44bd38cb217a45e6bf95009a08b7db83 |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-03-13T01:57:18Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-44bd38cb217a45e6bf95009a08b7db832023-07-02T11:06:40ZengBMCBMC Cardiovascular Disorders1471-22612023-06-0123111110.1186/s12872-023-03351-3Can the current monkeypox affect the heart? A systematic review of case series and case reportReem Sayad0Abdelmonem Siddiq1Ahmed Hashim2Ahmed Saad Elsaeidy3Faculty of Medicine, Assiut UniversityFaculty of Pharmacy, Mansoura UniversityFaculty of Medicine, Ain Shams UniversityFaculty of Medicine, Benha UniversityAbstract Background Monkeypox is a zoonotic viral infection first reported in May 2022. Monkeypox cases present with prodromal symptoms, rash, and/or systemic complications. This study systematically reviews the monkeypox cases presented with any cardiac complications. Methods A systematic literature search was done to locate papers that discuss any cardiac complications associated with monkeypox; then, data were analyzed qualitatively. Results Nine articles, including the 13 cases that reported cardiac complications of the disease, were included in the review. Five cases previously had sex with men, and two cases had unprotected intercourse, which reveals the importance of the sexual route in disease transmission. All cases have a wide spectrum of cardiac complications, such as acute myocarditis, pericarditis, pericardial effusion, and myopericarditis. Conclusion This study clarifies the potential for cardiac complications in monkeypox cases and provides avenues for future research to determine the underlying mechanism. Also, we found that the cases with pericarditis were treated with colchicine, and those with myocarditis were treated with supportive care or cardioprotective treatment (Bisoprolol and Ramipril). Furthermore, Tecovirimat is used as an antiviral drug for 14 days.https://doi.org/10.1186/s12872-023-03351-3MonkeypoxMpoxCardiomyopathyMyocarditisCarditisPericarditis |
| spellingShingle | Reem Sayad Abdelmonem Siddiq Ahmed Hashim Ahmed Saad Elsaeidy Can the current monkeypox affect the heart? A systematic review of case series and case report BMC Cardiovascular Disorders Monkeypox Mpox Cardiomyopathy Myocarditis Carditis Pericarditis |
| title | Can the current monkeypox affect the heart? A systematic review of case series and case report |
| title_full | Can the current monkeypox affect the heart? A systematic review of case series and case report |
| title_fullStr | Can the current monkeypox affect the heart? A systematic review of case series and case report |
| title_full_unstemmed | Can the current monkeypox affect the heart? A systematic review of case series and case report |
| title_short | Can the current monkeypox affect the heart? A systematic review of case series and case report |
| title_sort | can the current monkeypox affect the heart a systematic review of case series and case report |
| topic | Monkeypox Mpox Cardiomyopathy Myocarditis Carditis Pericarditis |
| url | https://doi.org/10.1186/s12872-023-03351-3 |
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