Single-cell ATAC-seq signal extraction and enhancement with SCATE
Abstract Single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) is the state-of-the-art technology for analyzing genome-wide regulatory landscapes in single cells. Single-cell ATAC-seq data are sparse and noisy, and analyzing such data is challenging. Existing computational m...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13059-020-02075-3 |