Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways

Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways

Summary: The angiotensin-converting enzyme 2 (ACE2) protein is a key catalytic regulator of the renin-angiotensin system (RAS), involved in fluid homeostasis and blood pressure modulation. ACE2 also serves as a cell-surface receptor for some coronaviruses such as SARS-CoV and SARS-CoV-2. Improved ch...

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Bibliographic Details
Main Authors: Daniel Richard, Pushpanathan Muthuirulan, Jennifer Aguiar, Andrew C. Doxey, Arinjay Banerjee, Karen Mossman, Jeremy Hirota, Terence D. Capellini
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Immunology
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222008860

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http://www.sciencedirect.com/science/article/pii/S2589004222008860

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