A Magtein<sup>®</sup>, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults
Magnesium is one of the most abundant essential minerals in the body. Magnesium supplements mostly have low bioavailability, except magnesium L-threonate. In 2010, a novel magnesium compound, magnesium L-threonate (Magtein<sup>®</sup>) was identified and was shown to raise the magnesium...
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| Format: | Article |
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MDPI AG
2022-12-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/24/5235 |
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| author | Chengxiang Zhang Qi Hu Shifen Li Feifei Dai Wen Qian Susan Hewlings Ting Yan Yubang Wang |
| author_facet | Chengxiang Zhang Qi Hu Shifen Li Feifei Dai Wen Qian Susan Hewlings Ting Yan Yubang Wang |
| author_sort | Chengxiang Zhang |
| collection | DOAJ |
| description | Magnesium is one of the most abundant essential minerals in the body. Magnesium supplements mostly have low bioavailability, except magnesium L-threonate. In 2010, a novel magnesium compound, magnesium L-threonate (Magtein<sup>®</sup>) was identified and was shown to raise the magnesium levels in the brain and neurons effectively. In this double-blind, placebo-controlled study, Magtein<sup>®</sup>PS, a magnesium L-threonate (Magtein<sup>®</sup>)- and phosphatidylserine-based formulation additionally containing vitamins C and D, was tested for its cognitive benefits in 109 healthy Chinese adults aged 18–65 years. Subjects were randomly assigned to receive either Magtein<sup>®</sup>PS or placebo (starch) capsules, at a dose of 2 g/day. “The Clinical Memory Test”, the standard test commonly used in Chinese hospitals and academic institutes for cognitive evaluation, was administered before and 30 days after subjects received the supplement. Subjects receiving Magtein<sup>®</sup>PS showed significant improvements over the control group in all five subcategories of “The Clinical Memory Test” as well as the overall memory quotient scores. The older participants showed more improvement than younger participants. Results indicated significant benefits of Magtein<sup>®</sup>PS in improving memory and cognition in healthy Chinese adults. |
| first_indexed | 2024-03-09T16:00:10Z |
| format | Article |
| id | doaj.art-44c47b4c2a244098908d6ed1574995ef |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T16:00:10Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-44c47b4c2a244098908d6ed1574995ef2023-11-24T17:07:46ZengMDPI AGNutrients2072-66432022-12-011424523510.3390/nu14245235A Magtein<sup>®</sup>, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese AdultsChengxiang Zhang0Qi Hu1Shifen Li2Feifei Dai3Wen Qian4Susan Hewlings5Ting Yan6Yubang Wang7The Key Laboratory of Modern Toxicology, Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 210029, ChinaThe Key Laboratory of Modern Toxicology, Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 210029, ChinaThe Key Laboratory of Modern Toxicology, Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 210029, ChinaThe Key Laboratory of Modern Toxicology, Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 210029, ChinaThe Key Laboratory of Modern Toxicology, Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 210029, ChinaNutrasoource 120 Research La, Guelph, ON N1G 0B4, CanadaThe Key Laboratory of Modern Toxicology, Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 210029, ChinaThe Key Laboratory of Modern Toxicology, Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 210029, ChinaMagnesium is one of the most abundant essential minerals in the body. Magnesium supplements mostly have low bioavailability, except magnesium L-threonate. In 2010, a novel magnesium compound, magnesium L-threonate (Magtein<sup>®</sup>) was identified and was shown to raise the magnesium levels in the brain and neurons effectively. In this double-blind, placebo-controlled study, Magtein<sup>®</sup>PS, a magnesium L-threonate (Magtein<sup>®</sup>)- and phosphatidylserine-based formulation additionally containing vitamins C and D, was tested for its cognitive benefits in 109 healthy Chinese adults aged 18–65 years. Subjects were randomly assigned to receive either Magtein<sup>®</sup>PS or placebo (starch) capsules, at a dose of 2 g/day. “The Clinical Memory Test”, the standard test commonly used in Chinese hospitals and academic institutes for cognitive evaluation, was administered before and 30 days after subjects received the supplement. Subjects receiving Magtein<sup>®</sup>PS showed significant improvements over the control group in all five subcategories of “The Clinical Memory Test” as well as the overall memory quotient scores. The older participants showed more improvement than younger participants. Results indicated significant benefits of Magtein<sup>®</sup>PS in improving memory and cognition in healthy Chinese adults.https://www.mdpi.com/2072-6643/14/24/5235magnesium L-threonatemagnesiumMagtein<sup>®</sup>Magtein<sup>®</sup>PSmemorycognition |
| spellingShingle | Chengxiang Zhang Qi Hu Shifen Li Feifei Dai Wen Qian Susan Hewlings Ting Yan Yubang Wang A Magtein<sup>®</sup>, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults Nutrients magnesium L-threonate magnesium Magtein<sup>®</sup> Magtein<sup>®</sup>PS memory cognition |
| title | A Magtein<sup>®</sup>, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults |
| title_full | A Magtein<sup>®</sup>, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults |
| title_fullStr | A Magtein<sup>®</sup>, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults |
| title_full_unstemmed | A Magtein<sup>®</sup>, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults |
| title_short | A Magtein<sup>®</sup>, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults |
| title_sort | magtein sup r sup magnesium l threonate based formula improves brain cognitive functions in healthy chinese adults |
| topic | magnesium L-threonate magnesium Magtein<sup>®</sup> Magtein<sup>®</sup>PS memory cognition |
| url | https://www.mdpi.com/2072-6643/14/24/5235 |
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