Cilioretinal Arteries in Highly Myopic Eyes: A Photographic Classification System and Its Association With Myopic Macular Degeneration
Purpose: To develop a photographic classification for cilioretinal arteries and to investigate its association with myopic macular degeneration (MMD).Methods: One thousand six hundred ninety-two highly myopic eyes of 1,692 patients were included. The presence of a cilioretinal artery was determined...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-12-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2020.595544/full |
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| author | Jiaqi Meng Ling Wei Keke Zhang Keke Zhang Keke Zhang Keke Zhang Wenwen He Wenwen He Wenwen He Wenwen He Yi Lu Yi Lu Yi Lu Yi Lu Xiangjia Zhu Xiangjia Zhu Xiangjia Zhu Xiangjia Zhu |
| author_facet | Jiaqi Meng Ling Wei Keke Zhang Keke Zhang Keke Zhang Keke Zhang Wenwen He Wenwen He Wenwen He Wenwen He Yi Lu Yi Lu Yi Lu Yi Lu Xiangjia Zhu Xiangjia Zhu Xiangjia Zhu Xiangjia Zhu |
| author_sort | Jiaqi Meng |
| collection | DOAJ |
| description | Purpose: To develop a photographic classification for cilioretinal arteries and to investigate its association with myopic macular degeneration (MMD).Methods: One thousand six hundred ninety-two highly myopic eyes of 1,692 patients were included. The presence of a cilioretinal artery was determined by fundus photographs, and a photographic classification was proposed. MMD was classified according to the International META-PM Classification. Associations of the cilioretinal artery and its classifications with MMD and visual acuity were analyzed.Results: Of the eyes tested, 245 (14.5%) had a cilioretinal artery. The cilioretinal arteries were classified into four categories (temporal “cake-fork,” 35.92%; temporal “ribbon,” 53.47%; “multiple,” 6.53%; “nasal,” 4.08%) and 3 distributions based on whether its visible branches reached the central foveal area. Eyes with cilioretinal arteries had significantly less MMD of grade ≥3 and better visual acuity than those without (P < 0.01). Multiple linear regression analysis showed that younger age, male sex, shorter axial length, and the presence of a cilioretinal artery were associated with better visual acuity in highly myopic eyes (all P < 0.05). The “nasal” category presented more MMD with grade ≥3 and worse visual acuity than the other categories (P < 0.05), whereas the “multiple” category contained no eyes with MMD grade ≥3. The cilioretinal arteries reaching the central foveal area showed less MMD of grade ≥3 and better visual acuity than those not (P < 0.05).Conclusions: We propose a photographic classification for cilioretinal arteries that has good clinical relevance to visual functions. The cilioretinal artery may potentially afford protection against MMD. |
| first_indexed | 2024-12-21T13:25:35Z |
| format | Article |
| id | doaj.art-44c670d3bc16424ba6f51d906583331c |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-12-21T13:25:35Z |
| publishDate | 2020-12-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Medicine |
| spelling | doaj.art-44c670d3bc16424ba6f51d906583331c2022-12-21T19:02:28ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2020-12-01710.3389/fmed.2020.595544595544Cilioretinal Arteries in Highly Myopic Eyes: A Photographic Classification System and Its Association With Myopic Macular DegenerationJiaqi Meng0Ling Wei1Keke Zhang2Keke Zhang3Keke Zhang4Keke Zhang5Wenwen He6Wenwen He7Wenwen He8Wenwen He9Yi Lu10Yi Lu11Yi Lu12Yi Lu13Xiangjia Zhu14Xiangjia Zhu15Xiangjia Zhu16Xiangjia Zhu17Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, ChinaNational Health Commission Key Laboratory of Myopia (Fudan University), Shanghai, ChinaKey Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, ChinaShanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, ChinaNational Health Commission Key Laboratory of Myopia (Fudan University), Shanghai, ChinaKey Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, ChinaShanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, ChinaNational Health Commission Key Laboratory of Myopia (Fudan University), Shanghai, ChinaKey Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, ChinaShanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, ChinaNational Health Commission Key Laboratory of Myopia (Fudan University), Shanghai, ChinaKey Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, ChinaShanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, ChinaPurpose: To develop a photographic classification for cilioretinal arteries and to investigate its association with myopic macular degeneration (MMD).Methods: One thousand six hundred ninety-two highly myopic eyes of 1,692 patients were included. The presence of a cilioretinal artery was determined by fundus photographs, and a photographic classification was proposed. MMD was classified according to the International META-PM Classification. Associations of the cilioretinal artery and its classifications with MMD and visual acuity were analyzed.Results: Of the eyes tested, 245 (14.5%) had a cilioretinal artery. The cilioretinal arteries were classified into four categories (temporal “cake-fork,” 35.92%; temporal “ribbon,” 53.47%; “multiple,” 6.53%; “nasal,” 4.08%) and 3 distributions based on whether its visible branches reached the central foveal area. Eyes with cilioretinal arteries had significantly less MMD of grade ≥3 and better visual acuity than those without (P < 0.01). Multiple linear regression analysis showed that younger age, male sex, shorter axial length, and the presence of a cilioretinal artery were associated with better visual acuity in highly myopic eyes (all P < 0.05). The “nasal” category presented more MMD with grade ≥3 and worse visual acuity than the other categories (P < 0.05), whereas the “multiple” category contained no eyes with MMD grade ≥3. The cilioretinal arteries reaching the central foveal area showed less MMD of grade ≥3 and better visual acuity than those not (P < 0.05).Conclusions: We propose a photographic classification for cilioretinal arteries that has good clinical relevance to visual functions. The cilioretinal artery may potentially afford protection against MMD.https://www.frontiersin.org/articles/10.3389/fmed.2020.595544/fullcilioretinal arterymyopic macular degenerationhigh myopiafundus photographyvisual acuity |
| spellingShingle | Jiaqi Meng Ling Wei Keke Zhang Keke Zhang Keke Zhang Keke Zhang Wenwen He Wenwen He Wenwen He Wenwen He Yi Lu Yi Lu Yi Lu Yi Lu Xiangjia Zhu Xiangjia Zhu Xiangjia Zhu Xiangjia Zhu Cilioretinal Arteries in Highly Myopic Eyes: A Photographic Classification System and Its Association With Myopic Macular Degeneration Frontiers in Medicine cilioretinal artery myopic macular degeneration high myopia fundus photography visual acuity |
| title | Cilioretinal Arteries in Highly Myopic Eyes: A Photographic Classification System and Its Association With Myopic Macular Degeneration |
| title_full | Cilioretinal Arteries in Highly Myopic Eyes: A Photographic Classification System and Its Association With Myopic Macular Degeneration |
| title_fullStr | Cilioretinal Arteries in Highly Myopic Eyes: A Photographic Classification System and Its Association With Myopic Macular Degeneration |
| title_full_unstemmed | Cilioretinal Arteries in Highly Myopic Eyes: A Photographic Classification System and Its Association With Myopic Macular Degeneration |
| title_short | Cilioretinal Arteries in Highly Myopic Eyes: A Photographic Classification System and Its Association With Myopic Macular Degeneration |
| title_sort | cilioretinal arteries in highly myopic eyes a photographic classification system and its association with myopic macular degeneration |
| topic | cilioretinal artery myopic macular degeneration high myopia fundus photography visual acuity |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2020.595544/full |
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