Eco-Friendly Synthesis and Antiproliferative Evaluation of Some Oxygen Substituted Diaryl Ketones

Eco-Friendly Synthesis and Antiproliferative Evaluation of Some Oxygen Substituted Diaryl Ketones

A broad variety of oxygen-substituted diaryl ketones has been synthesized by solar energy-induced Friedel Crafts acylations of 1,4-benzo- and 1,4-naphthoquinones with benzaldehydes. The in vitro antiproliferative properties of the photoproducts were assessed on prostate (DU-145), bladder (T24) and b...

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Bibliographic Details
Main Authors: Jaime A. Valderrama, Pedro Buc Calderon, Giulio G. Muccioli, Paola Arenas, Andrés Peña, David Ríos, Julio Benites
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Molecules
Subjects:
photo-Friedel Crafts acylation
diaryl ketones
green chemistry
antiproliferative activity
Online Access:http://www.mdpi.com/1420-3049/18/8/9818

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