Anti-CD123 antibody-modified niosomes for targeted delivery of daunorubicin against acute myeloid leukemia

Anti-CD123 antibody-modified niosomes for targeted delivery of daunorubicin against acute myeloid leukemia

A novel niosomal delivery system was designed and investigated for the targeted delivery of daunorubicin (DNR) against acute myeloid leukemia (AML). Anti-CD123 antibodies conjugated to Mal-PEG2000-DSPE were incorporated into normal niosomes (NS) via a post insertion method to afford antibody-modifie...

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Bibliographic Details
Main Authors: Fu-rong Liu, Hui Jin, Yin Wang, Chen Chen, Ming Li, Sheng-jun Mao, Qiantao Wang, Hui Li
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
niosome
cd123
drug targeting
acute myeloid leukemia
daunorubicin
Online Access:http://dx.doi.org/10.1080/10717544.2017.1333170

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