Self-restoration of cardiac excitation rhythm by anti-arrhythmic ion channel gating

Self-restoration of cardiac excitation rhythm by anti-arrhythmic ion channel gating

Homeostatic regulation protects organisms against hazardous physiological changes. However, such regulation is limited in certain organs and associated biological processes. For example, the heart fails to self-restore its normal electrical activity once disturbed, as with sustained arrhythmias. Her...

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Bibliographic Details
Main Authors: Rupamanjari Majumder, Tim De Coster, Nina Kudryashova, Arie O Verkerk, Ivan V Kazbanov, Balázs Ördög, Niels Harlaar, Ronald Wilders, Antoine AF de Vries, Dirk L Ypey, Alexander V Panfilov, Daniël A Pijnappels
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
rhythm disturbances
defibrillation
ion channels
gating properties
computer modelling
dynamic patch clamp
Online Access:https://elifesciences.org/articles/55921

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