Herbal Fixed Dose Combinations in Nepal: Growing Concerns in a Developing Country
Herbal medicines are mostly prepared as a combination therapy that has been used since therapeutic was first practiced. Combination products, also known as Fixed Dose Combinations (FDCs) of herbal remedies are in widespread use in Nepal. Herbal FDCs are in common practice because it is believed to...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2016-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/8686/20519_CE(RA1)_F(T)_PF1(T_AS)_PFA(P)_PF2(PAG).pdf |
| _version_ | 1818896882931335168 |
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| author | Arjun Poudel Kadir Alam Subish Palaian Mohamed Izham Mohamed Ibrahim |
| author_facet | Arjun Poudel Kadir Alam Subish Palaian Mohamed Izham Mohamed Ibrahim |
| author_sort | Arjun Poudel |
| collection | DOAJ |
| description | Herbal medicines are mostly prepared as a combination therapy that has been used since therapeutic was first practiced. Combination
products, also known as Fixed Dose Combinations (FDCs) of herbal remedies are in widespread use in Nepal. Herbal FDCs are in
common practice because it is believed to have better adherence, less side effects and easy accessibility. Nevertheless, combination
products possess greater risk of adverse effects, increases costs associated with treatments and leads to an ineffective dosages.
Herbal FDCs are used extensively in Nepal although the rationality beyond the use of these combinations is still unidentified and at times
are questionable. Legislations governing the use of herbal medicines is lacking in Nepal. Many herbal FDCs are not supported by any
scientific data and test for the presence of ingredients mentioned in the package insert/container label is always difficult. A FDC of herbal
products must be based on clear criteria that guarantee consumer safety and appropriate indications. These criteria helps to protect the
consumers or patients from the misleading claims and risk associated with the use of unjustifiable combination of herbal substances.
Strict monitoring from the regulatory body and the public awareness on the cost as well as advantages and disadvantages of herbal
FDCs is urgently required. |
| first_indexed | 2024-12-19T19:07:21Z |
| format | Article |
| id | doaj.art-44d939436fd24206b73ac14044438a1f |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-19T19:07:21Z |
| publishDate | 2016-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-44d939436fd24206b73ac14044438a1f2022-12-21T20:09:24ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-10-011010FM01FM0310.7860/JCDR/2016/20519.8686Herbal Fixed Dose Combinations in Nepal: Growing Concerns in a Developing CountryArjun Poudel0Kadir Alam1Subish Palaian2Mohamed Izham Mohamed Ibrahim3Research Associate, School of Clinical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Australia.Associate Professor, Department of Clinical Pharmacology and Therapeutics, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.Associate Professor, Department of Pharmacy Practice, College of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates. Professor, Department of Social and Administrative Pharmacy, College of Pharmacy, Qatar University, Doha, Qatar.Herbal medicines are mostly prepared as a combination therapy that has been used since therapeutic was first practiced. Combination products, also known as Fixed Dose Combinations (FDCs) of herbal remedies are in widespread use in Nepal. Herbal FDCs are in common practice because it is believed to have better adherence, less side effects and easy accessibility. Nevertheless, combination products possess greater risk of adverse effects, increases costs associated with treatments and leads to an ineffective dosages. Herbal FDCs are used extensively in Nepal although the rationality beyond the use of these combinations is still unidentified and at times are questionable. Legislations governing the use of herbal medicines is lacking in Nepal. Many herbal FDCs are not supported by any scientific data and test for the presence of ingredients mentioned in the package insert/container label is always difficult. A FDC of herbal products must be based on clear criteria that guarantee consumer safety and appropriate indications. These criteria helps to protect the consumers or patients from the misleading claims and risk associated with the use of unjustifiable combination of herbal substances. Strict monitoring from the regulatory body and the public awareness on the cost as well as advantages and disadvantages of herbal FDCs is urgently required.https://jcdr.net/articles/PDF/8686/20519_CE(RA1)_F(T)_PF1(T_AS)_PFA(P)_PF2(PAG).pdfcombination therapyherbal medicinesirrational drug use |
| spellingShingle | Arjun Poudel Kadir Alam Subish Palaian Mohamed Izham Mohamed Ibrahim Herbal Fixed Dose Combinations in Nepal: Growing Concerns in a Developing Country Journal of Clinical and Diagnostic Research combination therapy herbal medicines irrational drug use |
| title | Herbal Fixed Dose Combinations in Nepal: Growing Concerns in a Developing Country |
| title_full | Herbal Fixed Dose Combinations in Nepal: Growing Concerns in a Developing Country |
| title_fullStr | Herbal Fixed Dose Combinations in Nepal: Growing Concerns in a Developing Country |
| title_full_unstemmed | Herbal Fixed Dose Combinations in Nepal: Growing Concerns in a Developing Country |
| title_short | Herbal Fixed Dose Combinations in Nepal: Growing Concerns in a Developing Country |
| title_sort | herbal fixed dose combinations in nepal growing concerns in a developing country |
| topic | combination therapy herbal medicines irrational drug use |
| url | https://jcdr.net/articles/PDF/8686/20519_CE(RA1)_F(T)_PF1(T_AS)_PFA(P)_PF2(PAG).pdf |
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