Multi-Omics and Genome Editing Studies on Plant Cell Walls to Improve Biomass Quality
Biomass is one of the most important sources of renewable energy and plays an important role in reducing our reliance on fossil fuels. Efficient biomass production is essential to obtain large amounts of sustainable energy with minimal environmental cost. However, the biochemical and molecular proce...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Agriculture |
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| Online Access: | https://www.mdpi.com/2077-0472/13/4/752 |
| _version_ | 1797606845230088192 |
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| author | Tiziana Maria Sirangelo Richard Andrew Ludlow Tatiana Chenet Luisa Pasti Natasha Damiana Spadafora |
| author_facet | Tiziana Maria Sirangelo Richard Andrew Ludlow Tatiana Chenet Luisa Pasti Natasha Damiana Spadafora |
| author_sort | Tiziana Maria Sirangelo |
| collection | DOAJ |
| description | Biomass is one of the most important sources of renewable energy and plays an important role in reducing our reliance on fossil fuels. Efficient biomass production is essential to obtain large amounts of sustainable energy with minimal environmental cost. However, the biochemical and molecular processes behind the synthesis of the main components of biomass are still not fully understood. This review provides a comprehensive summary of the most relevant studies on cell wall biosynthesis and degradation mechanisms, focusing on the lignocellulosic component, in which the conversion process to fermentable sugars is expensive, due to its recalcitrant nature. A focus is placed on multi-omics research involving genomics, transcriptomics, proteomics, metabolomics, and phenomics, since multi-omics approaches offer a unique opportunity to investigate the biological pathways underlying the genotype traits characterizing cell wall energy crops. Furthermore, our study highlights the advances in genome editing approaches and proposes the modification of the genes that are involved in the complex cell wall structure as a feasible solution to an efficient biomass production. Several key points for future research activities based on these emerging technologies are also discussed, focusing on the combination of multi-omics and gene editing approaches, which offer potential for improved biomass valorization and the development of tangible bioproducts. |
| first_indexed | 2024-03-11T05:20:44Z |
| format | Article |
| id | doaj.art-44e39708452b4162945fa2c2ebd8218e |
| institution | Directory Open Access Journal |
| issn | 2077-0472 |
| language | English |
| last_indexed | 2024-03-11T05:20:44Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Agriculture |
| spelling | doaj.art-44e39708452b4162945fa2c2ebd8218e2023-11-17T17:52:55ZengMDPI AGAgriculture2077-04722023-03-0113475210.3390/agriculture13040752Multi-Omics and Genome Editing Studies on Plant Cell Walls to Improve Biomass QualityTiziana Maria Sirangelo0Richard Andrew Ludlow1Tatiana Chenet2Luisa Pasti3Natasha Damiana Spadafora4CREA—Council for Agricultural Research and Agricultural Economy Analysis, Genomics and Bioinformatics Department, 26836 Montanaso Lombardo, ItalySchool of Biosciences, Cardiff University, Sir Martin Evans Building, Museum Avenue, Cardiff CF10 3AX, UKDepartment of Environment and Prevention Sciences, University of Ferrara, 44121 Ferrara, ItalyDepartment of Environment and Prevention Sciences, University of Ferrara, 44121 Ferrara, ItalyDepartment of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, ItalyBiomass is one of the most important sources of renewable energy and plays an important role in reducing our reliance on fossil fuels. Efficient biomass production is essential to obtain large amounts of sustainable energy with minimal environmental cost. However, the biochemical and molecular processes behind the synthesis of the main components of biomass are still not fully understood. This review provides a comprehensive summary of the most relevant studies on cell wall biosynthesis and degradation mechanisms, focusing on the lignocellulosic component, in which the conversion process to fermentable sugars is expensive, due to its recalcitrant nature. A focus is placed on multi-omics research involving genomics, transcriptomics, proteomics, metabolomics, and phenomics, since multi-omics approaches offer a unique opportunity to investigate the biological pathways underlying the genotype traits characterizing cell wall energy crops. Furthermore, our study highlights the advances in genome editing approaches and proposes the modification of the genes that are involved in the complex cell wall structure as a feasible solution to an efficient biomass production. Several key points for future research activities based on these emerging technologies are also discussed, focusing on the combination of multi-omics and gene editing approaches, which offer potential for improved biomass valorization and the development of tangible bioproducts.https://www.mdpi.com/2077-0472/13/4/752energy cropsgenome editinggenomicsmetabolomicsphenomicsproteomics |
| spellingShingle | Tiziana Maria Sirangelo Richard Andrew Ludlow Tatiana Chenet Luisa Pasti Natasha Damiana Spadafora Multi-Omics and Genome Editing Studies on Plant Cell Walls to Improve Biomass Quality Agriculture energy crops genome editing genomics metabolomics phenomics proteomics |
| title | Multi-Omics and Genome Editing Studies on Plant Cell Walls to Improve Biomass Quality |
| title_full | Multi-Omics and Genome Editing Studies on Plant Cell Walls to Improve Biomass Quality |
| title_fullStr | Multi-Omics and Genome Editing Studies on Plant Cell Walls to Improve Biomass Quality |
| title_full_unstemmed | Multi-Omics and Genome Editing Studies on Plant Cell Walls to Improve Biomass Quality |
| title_short | Multi-Omics and Genome Editing Studies on Plant Cell Walls to Improve Biomass Quality |
| title_sort | multi omics and genome editing studies on plant cell walls to improve biomass quality |
| topic | energy crops genome editing genomics metabolomics phenomics proteomics |
| url | https://www.mdpi.com/2077-0472/13/4/752 |
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