Systems biology informed neural networks (SBINN) predict response and novel combinations for PD-1 checkpoint blockade
Michelle Przedborski et al. report an integrative systems biology and machine learning method for predicting cancer patient responses to immunotherapy treatment. Using their method, they identify several new drug combinations that could potentially improve treatment protocols for immunotherapy.
Main Authors: | Michelle Przedborski, Munisha Smalley, Saravanan Thiyagarajan, Aaron Goldman, Mohammad Kohandel |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-07-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02393-7 |
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