OX40L/OX40 Signal Promotes IL-9 Production by Mucosal MAIT Cells During Helicobacter pylori Infection

OX40L/OX40 Signal Promotes IL-9 Production by Mucosal MAIT Cells During Helicobacter pylori Infection

Mucosal associated invariant T (MAIT) cells play a critical role in Helicobacter pylori (H. pylori)-induced gastritis by promoting mucosal inflammation and aggravating mucosal injuries (1, 2). However, the underlying mechanism and key molecules involved are still uncertain. Here we identified OX40,...

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Bibliographic Details
Main Authors: Siqi Ming, Mei Zhang, Zibin Liang, Chunna Li, Jianzhong He, Peiyu Chen, Shunxian Zhang, Xiaoli Niu, Shimei Deng, Lanlan Geng, Guoliang Zhang, Sitang Gong, Yongjian Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
MAIT cells
H. pylori
gastritis
IL-9
inflammation
OX40
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.626017/full

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