Development, Validation, and Application of the LC-MS/MS Method for Determination of 4-Acetamidobenzoic Acid in Pharmacokinetic Pilot Studies in Pigs

Development, Validation, and Application of the LC-MS/MS Method for Determination of 4-Acetamidobenzoic Acid in Pharmacokinetic Pilot Studies in Pigs

Each drug has pharmacokinetics that must be defined for the substance to be used in humans and animals. Currently, one of the basic analytical tools for pharmacokinetics studies is high-performance liquid chromatography coupled with mass spectrometry. For this analytical method to be fully reliable,...

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Bibliographic Details
Main Authors: Paulina Markowska, Zbigniew Procajło, Joanna Wolska, Jerzy Jan Jaroszewski, Hubert Ziółkowski
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
4-acetamidobenzoic acid
validation
pharmacokinetic
pigs
LC-MS/MS
Online Access:https://www.mdpi.com/1420-3049/26/15/4437

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