Loss of <i>Nnt</i> Increases Expression of Oxidative Phosphorylation Complexes in C57BL/6J Hearts

Loss of <i>Nnt</i> Increases Expression of Oxidative Phosphorylation Complexes in C57BL/6J Hearts

Nicotinamide nucleotide transhydrogenase (NNT) is a proton pump in the inner mitochondrial membrane that generates reducing equivalents in the form of NAPDH, which can be used for anabolic pathways or to remove reactive oxygen species (ROS). A number of studies have linked NNT dysfunction to cardiom...

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Bibliographic Details
Main Authors: Jack L. Williams, Charlotte L. Hall, Eirini Meimaridou, Lou A. Metherell
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
C57BL/6N
C57BL/6J
NNT
RNAseq
cardiomyopathy
cellular respiration
Online Access:https://www.mdpi.com/1422-0067/22/11/6101

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