Cerebral Sinus Vein Thrombosis and Gender: A Not Entirely Casual Relationship

Cerebral sinus venous thrombosis (CSVT) is a relatively rare acute disorder of cerebral circulation, but it can potentially be associated with serious sequelae and a poor prognosis. The neurological manifestations associated with it are often not adequately taken into consideration given the extreme...

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Main Authors: Tiziana Ciarambino, Pietro Crispino, Giovanni Minervini, Mauro Giordano
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/5/1280
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author Tiziana Ciarambino
Pietro Crispino
Giovanni Minervini
Mauro Giordano
author_facet Tiziana Ciarambino
Pietro Crispino
Giovanni Minervini
Mauro Giordano
author_sort Tiziana Ciarambino
collection DOAJ
description Cerebral sinus venous thrombosis (CSVT) is a relatively rare acute disorder of cerebral circulation, but it can potentially be associated with serious sequelae and a poor prognosis. The neurological manifestations associated with it are often not adequately taken into consideration given the extreme variability and nuances of its clinical presentation and given the need for radiological methods suitable for this type of diagnosis. CSVT is usually more common in women, but so far there are little data available in the literature on sex-specific characteristics regarding this pathology. CSVT is the result of multiple conditions and is therefore to be considered a multifactorial disease where at least one risk factor is present in over 80% of cases. From the literature, we learn that congenital or acquired prothrombotic states are to be considered extremely associated with the occurrence of an acute episode of CSVT and its recurrences. It is, therefore, necessary to fully know the origins and natural history of CSVT, in order to implement the diagnostic and therapeutic pathways of these neurological manifestations. In this report, we summarize the main causes of CSVT considering the possible influence of gender, bearing in mind that most of the causes listed above are pathological conditions closely linked to the female sex.
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spelling doaj.art-44f10e5287864b9ab02c4e66f80fa8012023-11-18T00:34:40ZengMDPI AGBiomedicines2227-90592023-04-01115128010.3390/biomedicines11051280Cerebral Sinus Vein Thrombosis and Gender: A Not Entirely Casual RelationshipTiziana Ciarambino0Pietro Crispino1Giovanni Minervini2Mauro Giordano3Internal Medicine Department, Hospital of Marcianise, ASL Caserta, 81024 Caserta, ItalyInternal Medicine Department, Hospital of Latina, ASL Latina, 04100 Latina, ItalyEmergency Department, Hospital of Lagonegro, AOR San Carlo, 85042 Lagonegro, ItalyAdvanced Medical and Surgical Sciences Department, University of Campania, L. Vanvitelli, 81100 Naples, ItalyCerebral sinus venous thrombosis (CSVT) is a relatively rare acute disorder of cerebral circulation, but it can potentially be associated with serious sequelae and a poor prognosis. The neurological manifestations associated with it are often not adequately taken into consideration given the extreme variability and nuances of its clinical presentation and given the need for radiological methods suitable for this type of diagnosis. CSVT is usually more common in women, but so far there are little data available in the literature on sex-specific characteristics regarding this pathology. CSVT is the result of multiple conditions and is therefore to be considered a multifactorial disease where at least one risk factor is present in over 80% of cases. From the literature, we learn that congenital or acquired prothrombotic states are to be considered extremely associated with the occurrence of an acute episode of CSVT and its recurrences. It is, therefore, necessary to fully know the origins and natural history of CSVT, in order to implement the diagnostic and therapeutic pathways of these neurological manifestations. In this report, we summarize the main causes of CSVT considering the possible influence of gender, bearing in mind that most of the causes listed above are pathological conditions closely linked to the female sex.https://www.mdpi.com/2227-9059/11/5/1280cerebral venous sinus thrombosisgender differencescirculationrisk factor
spellingShingle Tiziana Ciarambino
Pietro Crispino
Giovanni Minervini
Mauro Giordano
Cerebral Sinus Vein Thrombosis and Gender: A Not Entirely Casual Relationship
Biomedicines
cerebral venous sinus thrombosis
gender differences
circulation
risk factor
title Cerebral Sinus Vein Thrombosis and Gender: A Not Entirely Casual Relationship
title_full Cerebral Sinus Vein Thrombosis and Gender: A Not Entirely Casual Relationship
title_fullStr Cerebral Sinus Vein Thrombosis and Gender: A Not Entirely Casual Relationship
title_full_unstemmed Cerebral Sinus Vein Thrombosis and Gender: A Not Entirely Casual Relationship
title_short Cerebral Sinus Vein Thrombosis and Gender: A Not Entirely Casual Relationship
title_sort cerebral sinus vein thrombosis and gender a not entirely casual relationship
topic cerebral venous sinus thrombosis
gender differences
circulation
risk factor
url https://www.mdpi.com/2227-9059/11/5/1280
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AT pietrocrispino cerebralsinusveinthrombosisandgenderanotentirelycasualrelationship
AT giovanniminervini cerebralsinusveinthrombosisandgenderanotentirelycasualrelationship
AT maurogiordano cerebralsinusveinthrombosisandgenderanotentirelycasualrelationship