Pharmacogenomics of cisplatin‐induced neurotoxicities: Hearing loss, tinnitus, and peripheral sensory neuropathy

Pharmacogenomics of cisplatin‐induced neurotoxicities: Hearing loss, tinnitus, and peripheral sensory neuropathy

Abstract Purpose Cisplatin is a critical component of first‐line chemotherapy for several cancers, but causes peripheral sensory neuropathy, hearing loss, and tinnitus. We aimed to identify comorbidities for cisplatin‐induced neurotoxicities among large numbers of similarly treated patients without...

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Bibliographische Detailangaben
Hauptverfasser: Xindi Zhang, Matthew R. Trendowski, Emma Wilkinson, Mohammad Shahbazi, Paul C. Dinh, Megan M. Shuey, Regeneron Genetics Center, Darren R. Feldman, Robert J. Hamilton, David J. Vaughn, Chunkit Fung, Christian Kollmannsberger, Robert Huddart, Neil E. Martin, Victoria A. Sanchez, Robert D. Frisina, Lawrence H. Einhorn, Nancy J. Cox, Lois B. Travis, M. Eileen Dolan
Format: Artikel
Sprache:English
Veröffentlicht: Wiley 2022-07-01
Schriftenreihe:Cancer Medicine
Schlagworte:
cisplatin
GWAS
ototoxicity
survivorship
neurotoxicity
testicular cancer
Online Zugang:https://doi.org/10.1002/cam4.4644

Online

https://doi.org/10.1002/cam4.4644

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