Comparing the Effect of Subcutaneous and Intravenous Tramadol Injection on Postoperative Pain
• Background: Recently it is suggested that local injection of tramadol can reduce postoperative pain; but it is controversial whether the intravenous injection is more perfect or subcutaneous. We conducted this study to compare the effect of these methods on postoperative pain. • Methods: In a pros...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | fas |
| Published: |
Isfahan University of Medical Sciences
2011-03-01
|
| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/664 |
| _version_ | 1827848662653337600 |
|---|---|
| author | Hamid Hajigholam Hajigholam Saryazdi Seyed Morteza Heidari Mohammad Golparvar Mahboobeh Rahbari |
| author_facet | Hamid Hajigholam Hajigholam Saryazdi Seyed Morteza Heidari Mohammad Golparvar Mahboobeh Rahbari |
| author_sort | Hamid Hajigholam Hajigholam Saryazdi |
| collection | DOAJ |
| description | • Background: Recently it is suggested that local injection of tramadol can reduce postoperative pain; but it is controversial whether the intravenous injection is more perfect or subcutaneous. We conducted this study to compare the effect of these methods on postoperative pain.
• Methods: In a prospective randomized double blind clinical trial study, 75 patients undergoing abdominal surgery were allocated in three groups (n = 25). In group A (subcutaneous), 1.5 mg/kg tramadol was injected subcutaneously and normal saline was injected intravenous in an equal volume of 10 cc; in group B (intravenous) 1.5 mg/kg tramadol was injected intravenous and normal saline was injected subcutaneously in an equal volume of 10 cc;and in group C (control) normal saline was injected subcutaneously and intravenous in an volume of 10 cc. The drugs were injected before incision of surgery in all groups. The severity of postoperative pain after surgery was evaluated by visual analogue scale and the time of first opioid analgesic used and total analgesic dose taken during the postoperative period was recorded.
• Finding: The total dose of used opioid analgesic was significantly less in subcutaneously injected tramadol group (P < 0.01). The time of the first opioid analgesic consumption was significantly shorter in control group (P < 0.01).
• Conclusion: According to results of this study, subcutaneous and intravenous injection of tramadol can reduce postoperative pain; subcutaneous injection was more effective, of course. Therefore, subcutaneous tramadol is suggested for control of postoperative pain. |
| first_indexed | 2024-03-12T09:51:07Z |
| format | Article |
| id | doaj.art-44f2c2d8f785453fba3c1645e4688909 |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T09:51:07Z |
| publishDate | 2011-03-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-44f2c2d8f785453fba3c1645e46889092023-09-02T12:29:01ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2011-03-0128113745751464Comparing the Effect of Subcutaneous and Intravenous Tramadol Injection on Postoperative PainHamid Hajigholam Hajigholam Saryazdi0Seyed Morteza Heidari1Mohammad Golparvar2Mahboobeh Rahbari3Assistant Professor, Department of Anesthesiology, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.Assistant Professor, Department of Anesthesiology, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.Assistant Professor, Department of Anesthesiology, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.Student of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran• Background: Recently it is suggested that local injection of tramadol can reduce postoperative pain; but it is controversial whether the intravenous injection is more perfect or subcutaneous. We conducted this study to compare the effect of these methods on postoperative pain. • Methods: In a prospective randomized double blind clinical trial study, 75 patients undergoing abdominal surgery were allocated in three groups (n = 25). In group A (subcutaneous), 1.5 mg/kg tramadol was injected subcutaneously and normal saline was injected intravenous in an equal volume of 10 cc; in group B (intravenous) 1.5 mg/kg tramadol was injected intravenous and normal saline was injected subcutaneously in an equal volume of 10 cc;and in group C (control) normal saline was injected subcutaneously and intravenous in an volume of 10 cc. The drugs were injected before incision of surgery in all groups. The severity of postoperative pain after surgery was evaluated by visual analogue scale and the time of first opioid analgesic used and total analgesic dose taken during the postoperative period was recorded. • Finding: The total dose of used opioid analgesic was significantly less in subcutaneously injected tramadol group (P < 0.01). The time of the first opioid analgesic consumption was significantly shorter in control group (P < 0.01). • Conclusion: According to results of this study, subcutaneous and intravenous injection of tramadol can reduce postoperative pain; subcutaneous injection was more effective, of course. Therefore, subcutaneous tramadol is suggested for control of postoperative pain.http://jims.mui.ac.ir/index.php/jims/article/view/664TramadolIntradermal injectionIntravenous injectionPostoperative pain |
| spellingShingle | Hamid Hajigholam Hajigholam Saryazdi Seyed Morteza Heidari Mohammad Golparvar Mahboobeh Rahbari Comparing the Effect of Subcutaneous and Intravenous Tramadol Injection on Postoperative Pain مجله دانشکده پزشکی اصفهان Tramadol Intradermal injection Intravenous injection Postoperative pain |
| title | Comparing the Effect of Subcutaneous and Intravenous Tramadol Injection on Postoperative Pain |
| title_full | Comparing the Effect of Subcutaneous and Intravenous Tramadol Injection on Postoperative Pain |
| title_fullStr | Comparing the Effect of Subcutaneous and Intravenous Tramadol Injection on Postoperative Pain |
| title_full_unstemmed | Comparing the Effect of Subcutaneous and Intravenous Tramadol Injection on Postoperative Pain |
| title_short | Comparing the Effect of Subcutaneous and Intravenous Tramadol Injection on Postoperative Pain |
| title_sort | comparing the effect of subcutaneous and intravenous tramadol injection on postoperative pain |
| topic | Tramadol Intradermal injection Intravenous injection Postoperative pain |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/664 |
| work_keys_str_mv | AT hamidhajigholamhajigholamsaryazdi comparingtheeffectofsubcutaneousandintravenoustramadolinjectiononpostoperativepain AT seyedmortezaheidari comparingtheeffectofsubcutaneousandintravenoustramadolinjectiononpostoperativepain AT mohammadgolparvar comparingtheeffectofsubcutaneousandintravenoustramadolinjectiononpostoperativepain AT mahboobehrahbari comparingtheeffectofsubcutaneousandintravenoustramadolinjectiononpostoperativepain |