Pyridostigmine bromide elicits progressive and chronic impairments in the cholinergic anti-inflammatory pathway in the prefrontal cortex and hippocampus of male rats

Pyridostigmine bromide elicits progressive and chronic impairments in the cholinergic anti-inflammatory pathway in the prefrontal cortex and hippocampus of male rats

Gulf War Illness (GWI) is a multi-symptom illness that continues to affect over 250,000 American Gulf War veterans. The causes of GWI remain equivocal; however, prophylactic use of the acetylcholinesterase inhibitor pyridostigmine bromide (PB), and the stress of combat have been identified as two po...

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Bibliographic Details
Main Authors: H.E. Burzynski, V.A. Macht, J.L. Woodruff, J.N. Crawford, J.M. Erichsen, G.G. Piroli, C.A. Grillo, J.R. Fadel, L.P. Reagan
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Neurobiology of Stress
Subjects:
Acetylcholine
Stress
Cytokine
Neuroinflammation
Gulf War Illness
α7 nicotinic acetylcholine receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289522000212

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http://www.sciencedirect.com/science/article/pii/S2352289522000212

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