Simple and affordable soft brace application in dystrophic epidermolysis bullosa patients
BackgroundDystrophic epidermolysis bullosa (DEB) is a hereditary disease characterized by increased fragility of the epidermis and mucosa and is accompanied by blister formation following minor trauma. Repeated injuries cause contracture and scar formation, which can further result in hand deformity...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1189962/full |
| _version_ | 1827390775714906112 |
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| author | Chong Wu Xin-He Jiao |
| author_facet | Chong Wu Xin-He Jiao |
| author_sort | Chong Wu |
| collection | DOAJ |
| description | BackgroundDystrophic epidermolysis bullosa (DEB) is a hereditary disease characterized by increased fragility of the epidermis and mucosa and is accompanied by blister formation following minor trauma. Repeated injuries cause contracture and scar formation, which can further result in hand deformity, leading to a decline in hand ability and a lower quality of life. In this study, after the scar release of patients' hands, we developed a new and practical portable soft support, and evaluated its efficacy in delaying the scar contracture of hands after operation.MethodsAccording to the hand function scores, the patients were divided into two groups. Those with excellent and good grades were assigned to the open hand function group, and those with poor grades were allocated to the restricted hand function group. The primary conditions, the use of a postoperative soft brace, and some common factors in the two groups were compared to determine whether these parameters influence postoperative hand function.ResultsThere were no significant differences in age, gender, body mass index, ADL assessment index, albumin concentration, hemoglobin concentration, fasting blood glucose level, prothrombin time, and activated partial thromboplastin time between the two groups (p > 0.05). In contrast, there was a significant difference between the two groups in the use of soft braces following the operation (p < 0.05). The odds ratio of patients fixed with a brace compared with patients not fixed with soft braces was 11.01.ConclusionsSoft brace is a critical factor impacting the hand function of patients with dystrophic epidermolysis bullosa after scar contracture release in both hands. Indeed, a hand brace worn after the operation can delay the recurrence of scar contracture in both hands and offer patients a longer time to use their hands effectively. In addition, by restoring the appearance of patients' hands and some hand functions, patients' mental state and quality of life have been greatly improved. |
| first_indexed | 2024-03-08T16:57:41Z |
| format | Article |
| id | doaj.art-44f495a665d74a5ebd32ff85b96a31c5 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-03-08T16:57:41Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-44f495a665d74a5ebd32ff85b96a31c52024-01-04T17:15:52ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2024-01-011010.3389/fsurg.2023.11899621189962Simple and affordable soft brace application in dystrophic epidermolysis bullosa patientsChong Wu0Xin-He Jiao1The Fifth Clinical Medical College of HenanUniversity of Chinese Medicine (Zhengzhou People’s Hospital), Zhengzhou, Henan, ChinaDepartment of Plastic Surgery, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, ChinaBackgroundDystrophic epidermolysis bullosa (DEB) is a hereditary disease characterized by increased fragility of the epidermis and mucosa and is accompanied by blister formation following minor trauma. Repeated injuries cause contracture and scar formation, which can further result in hand deformity, leading to a decline in hand ability and a lower quality of life. In this study, after the scar release of patients' hands, we developed a new and practical portable soft support, and evaluated its efficacy in delaying the scar contracture of hands after operation.MethodsAccording to the hand function scores, the patients were divided into two groups. Those with excellent and good grades were assigned to the open hand function group, and those with poor grades were allocated to the restricted hand function group. The primary conditions, the use of a postoperative soft brace, and some common factors in the two groups were compared to determine whether these parameters influence postoperative hand function.ResultsThere were no significant differences in age, gender, body mass index, ADL assessment index, albumin concentration, hemoglobin concentration, fasting blood glucose level, prothrombin time, and activated partial thromboplastin time between the two groups (p > 0.05). In contrast, there was a significant difference between the two groups in the use of soft braces following the operation (p < 0.05). The odds ratio of patients fixed with a brace compared with patients not fixed with soft braces was 11.01.ConclusionsSoft brace is a critical factor impacting the hand function of patients with dystrophic epidermolysis bullosa after scar contracture release in both hands. Indeed, a hand brace worn after the operation can delay the recurrence of scar contracture in both hands and offer patients a longer time to use their hands effectively. In addition, by restoring the appearance of patients' hands and some hand functions, patients' mental state and quality of life have been greatly improved.https://www.frontiersin.org/articles/10.3389/fsurg.2023.1189962/fullepidermolysis bullosasurgical prognosishand functioninfluencing factorssoft brace |
| spellingShingle | Chong Wu Xin-He Jiao Simple and affordable soft brace application in dystrophic epidermolysis bullosa patients Frontiers in Surgery epidermolysis bullosa surgical prognosis hand function influencing factors soft brace |
| title | Simple and affordable soft brace application in dystrophic epidermolysis bullosa patients |
| title_full | Simple and affordable soft brace application in dystrophic epidermolysis bullosa patients |
| title_fullStr | Simple and affordable soft brace application in dystrophic epidermolysis bullosa patients |
| title_full_unstemmed | Simple and affordable soft brace application in dystrophic epidermolysis bullosa patients |
| title_short | Simple and affordable soft brace application in dystrophic epidermolysis bullosa patients |
| title_sort | simple and affordable soft brace application in dystrophic epidermolysis bullosa patients |
| topic | epidermolysis bullosa surgical prognosis hand function influencing factors soft brace |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1189962/full |
| work_keys_str_mv | AT chongwu simpleandaffordablesoftbraceapplicationindystrophicepidermolysisbullosapatients AT xinhejiao simpleandaffordablesoftbraceapplicationindystrophicepidermolysisbullosapatients |