Synaptotagmin-3 interactions with GluA2 mediate brain damage and impair functional recovery in stroke

Synaptotagmin-3 interactions with GluA2 mediate brain damage and impair functional recovery in stroke

Summary: Synaptotagmin III (Syt3) is a Ca2+-dependent membrane-traffic protein that is highly concentrated in synaptic plasma membranes and affects synaptic plasticity by regulating post-synaptic receptor endocytosis. Here, we show that Syt3 is upregulated in the penumbra after ischemia/reperfusion...

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Bibliographic Details
Main Authors: Haifeng Lu, Shujun Chen, Qianqian Nie, Qun Xue, Hua Fan, Yiqing Wang, Shenghao Fan, Juehua Zhu, Haitao Shen, Haiying Li, Qi Fang, Jianqiang Ni, Gang Chen
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723002449

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