Synaptotagmin-3 interactions with GluA2 mediate brain damage and impair functional recovery in stroke
Summary: Synaptotagmin III (Syt3) is a Ca2+-dependent membrane-traffic protein that is highly concentrated in synaptic plasma membranes and affects synaptic plasticity by regulating post-synaptic receptor endocytosis. Here, we show that Syt3 is upregulated in the penumbra after ischemia/reperfusion...
Main Authors: | Haifeng Lu, Shujun Chen, Qianqian Nie, Qun Xue, Hua Fan, Yiqing Wang, Shenghao Fan, Juehua Zhu, Haitao Shen, Haiying Li, Qi Fang, Jianqiang Ni, Gang Chen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-03-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723002449 |
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