Microneedle-Assisted Topical Delivery of Idebenone-Loaded Bioadhesive Nanoparticles Protect against UV-Induced Skin Damage

Microneedle-Assisted Topical Delivery of Idebenone-Loaded Bioadhesive Nanoparticles Protect against UV-Induced Skin Damage

Ultraviolet (UV) radiation can penetrate the basal layer of the skin and induce profound alterations in the underlying dermal tissues, including skin pigmentation, oxidative stress, photoaging, glycation, and skin cancer. Idebenone (IDB), an effective antioxidant that suppresses melanin biosynthesis...

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Bibliographic Details
Main Authors: Yuan Xie, Jingping Ye, Yaqi Ouyang, Jianing Gong, Chujie Li, Yang Deng, Yang Mai, Yang Liu, Wenbin Deng
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomedicines
Subjects:
UV-induced skin damage
idebenone
bioadhesive nanoparticles
microneedle
Online Access:https://www.mdpi.com/2227-9059/11/6/1649

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