Quality of life assessment in the late postoperative period of patients with rectal cancer submitted to total mesorectal excision
After the introduction of total mesorectal excision (TME) and radiochemotherapy, excel- lent results have been achieved in the treatment of patients with rectal cancer. With better oncologic control of the disease, the functional results of this type of therapeutic approach and their impact on the q...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações Ltda.
2013-04-01
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| Series: | Journal of Coloproctology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2237936313000208 |
| _version_ | 1818641263513042944 |
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| author | Paulo Rocha França Neto Fábio Lopes de Queiroz Isabella Rocha França Longo Staino Antônio Lacerda Filho |
| author_facet | Paulo Rocha França Neto Fábio Lopes de Queiroz Isabella Rocha França Longo Staino Antônio Lacerda Filho |
| author_sort | Paulo Rocha França Neto |
| collection | DOAJ |
| description | After the introduction of total mesorectal excision (TME) and radiochemotherapy, excel- lent results have been achieved in the treatment of patients with rectal cancer. With better oncologic control of the disease, the functional results of this type of therapeutic approach and their impact on the quality of life (QOL) of patients started to be increasingly valued. The aims of this study were to evaluate the QOL of patients with rectal cancer submitted to TME in the late postoperative period and the possible factors that directly influence their quality of life. A total of 72 patients submitted to TME due to extraperitoneal rectal tumor were assessed, after at least one postoperative year, by applying QOL question- naires (EORTC QLQ-C30 and EORTC QLQ-CR38), in addition to a specific clinical question- naire and rectal examination. Patients were evaluated regarding gender, age, indication of radiotherapy and chemotherapy preoperatively, length of postoperative period, distance from the anastomosis to the anal verge and general health status. The mean overall health status of patients was satisfactory (82.06). There was no difference in overall health sta- tus between patients with respect to gender, but the male patients had less insomnia (p = 0.002), better future prospects (p = 0.011), fewer effects of chemotherapy (p = 0.020) and better sexual function (p < 0.0001). Patients younger than 50 years had fewer urinary problems (p = 0.035), whereas those older than 65 years reported poorer sexual function (p = 0.012). Patients who underwent neoadjuvant therapy had more diarrhea (p = 0.012). Quality of life did not change significantly with time after surgery and the distance from the anastomosis to the anal verge. We conclude that patients undergoing TME have a good quality of life one year after the surgery and that the factors capable of affecting QOL should be identified and improved. Resumo: A introdução da cirurgia de excisão total do mesorreto (ETM) e da radioquimioterapia pro- piciaram excelentes resultados no tratamento do câncer de reto. Com o melhor controle oncológico da doença, os resultados funcionais deste tipo de abordagem terapêutica e seu impacto na qualidade de vida (QV) dos pacientes passaram a ser cada vez mais valo- rizados. Os objetivos do presente estudo foram avaliar a QV dos pacientes portadores de câncer retal submetidos à ETM, em pós-operatório tardio e os possíveis fatores capazes de influenciar diretamente na qualidade de vida dos mesmos. Foram avaliados 72 pa- cientes submetidos à ETM por tumor de reto extraperitoneal, com no mínimo, um ano de pós-operatório, por meio da aplicação de questionários de QV (EORTC QLQ-C30 e EORTC QLQ-CR38), além de questionário clínico específico e exame proctológico. Os pacientes foram avaliados quanto a gênero, idade, realização de radioterapia e quimioterapia pré-operatórias, tempo de pós-operatório, distância da anastomose à margem anal e estado global de saúde. A média do estado global de saúde dos pacientes avaliados foi satisfató- ria (82,06). Não se observou diferença na saúde global entre os pacientes com relação ao gênero, porém os pacientes do sexo masculino apresentaram menos insônia (p = 0,002), melhores perspectivas futuras (p = 0,011), menos efeitos da quimioterapia (p = 0,020) e melhor função sexual (p < 0,0001). Os pacientes com menos de 50 anos apresentaram menos problemas miccionais (p = 0,035), já os com mais de 65 anos relataram uma pior função sexual (p = 0,012). Os pacientes que realizaram neoadjuvância apresentaram mais diarreia (p = 0,012). A qualidade de vida não se alterou significativamente de acordo com o tempo de pós-operatório e distância da anastomose à margem anal. Conclui-se que os pacientes submetidos à ETM apresentam uma boa qualidade de vida após um ano de cirurgia e que os fatores envolvidos capazes de influenciar a QV devem ser identifica- dos e otimizados. Keywords: Quality of life, Rectal neoplasms, Colorectal surgery, Postoperative evaluation, Palavras-chave: Qualidade de vida, Neoplasias retais, Cirurgia colorretal, Pós-operatório |
| first_indexed | 2024-12-16T23:24:23Z |
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| id | doaj.art-44f772fc994e4355a0eb5e79be94f4e4 |
| institution | Directory Open Access Journal |
| issn | 2237-9363 |
| language | English |
| last_indexed | 2024-12-16T23:24:23Z |
| publishDate | 2013-04-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | Journal of Coloproctology |
| spelling | doaj.art-44f772fc994e4355a0eb5e79be94f4e42022-12-21T22:12:03ZengThieme Revinter Publicações Ltda.Journal of Coloproctology2237-93632013-04-013325057Quality of life assessment in the late postoperative period of patients with rectal cancer submitted to total mesorectal excisionPaulo Rocha França Neto0Fábio Lopes de Queiroz1Isabella Rocha França Longo Staino2Antônio Lacerda Filho3Coloproctology Clinic of Hospital Felício Rocho, Belo Horizonte, MG, Brazil; Corresponding author.Coloproctology Clinic of Hospital Felício Rocho, Belo Horizonte, MG, BrazilMedical School of Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, BrazilSurgery Departament of the Medical School of UFMG, Belo Horizonte, MG, BrazilAfter the introduction of total mesorectal excision (TME) and radiochemotherapy, excel- lent results have been achieved in the treatment of patients with rectal cancer. With better oncologic control of the disease, the functional results of this type of therapeutic approach and their impact on the quality of life (QOL) of patients started to be increasingly valued. The aims of this study were to evaluate the QOL of patients with rectal cancer submitted to TME in the late postoperative period and the possible factors that directly influence their quality of life. A total of 72 patients submitted to TME due to extraperitoneal rectal tumor were assessed, after at least one postoperative year, by applying QOL question- naires (EORTC QLQ-C30 and EORTC QLQ-CR38), in addition to a specific clinical question- naire and rectal examination. Patients were evaluated regarding gender, age, indication of radiotherapy and chemotherapy preoperatively, length of postoperative period, distance from the anastomosis to the anal verge and general health status. The mean overall health status of patients was satisfactory (82.06). There was no difference in overall health sta- tus between patients with respect to gender, but the male patients had less insomnia (p = 0.002), better future prospects (p = 0.011), fewer effects of chemotherapy (p = 0.020) and better sexual function (p < 0.0001). Patients younger than 50 years had fewer urinary problems (p = 0.035), whereas those older than 65 years reported poorer sexual function (p = 0.012). Patients who underwent neoadjuvant therapy had more diarrhea (p = 0.012). Quality of life did not change significantly with time after surgery and the distance from the anastomosis to the anal verge. We conclude that patients undergoing TME have a good quality of life one year after the surgery and that the factors capable of affecting QOL should be identified and improved. Resumo: A introdução da cirurgia de excisão total do mesorreto (ETM) e da radioquimioterapia pro- piciaram excelentes resultados no tratamento do câncer de reto. Com o melhor controle oncológico da doença, os resultados funcionais deste tipo de abordagem terapêutica e seu impacto na qualidade de vida (QV) dos pacientes passaram a ser cada vez mais valo- rizados. Os objetivos do presente estudo foram avaliar a QV dos pacientes portadores de câncer retal submetidos à ETM, em pós-operatório tardio e os possíveis fatores capazes de influenciar diretamente na qualidade de vida dos mesmos. Foram avaliados 72 pa- cientes submetidos à ETM por tumor de reto extraperitoneal, com no mínimo, um ano de pós-operatório, por meio da aplicação de questionários de QV (EORTC QLQ-C30 e EORTC QLQ-CR38), além de questionário clínico específico e exame proctológico. Os pacientes foram avaliados quanto a gênero, idade, realização de radioterapia e quimioterapia pré-operatórias, tempo de pós-operatório, distância da anastomose à margem anal e estado global de saúde. A média do estado global de saúde dos pacientes avaliados foi satisfató- ria (82,06). Não se observou diferença na saúde global entre os pacientes com relação ao gênero, porém os pacientes do sexo masculino apresentaram menos insônia (p = 0,002), melhores perspectivas futuras (p = 0,011), menos efeitos da quimioterapia (p = 0,020) e melhor função sexual (p < 0,0001). Os pacientes com menos de 50 anos apresentaram menos problemas miccionais (p = 0,035), já os com mais de 65 anos relataram uma pior função sexual (p = 0,012). Os pacientes que realizaram neoadjuvância apresentaram mais diarreia (p = 0,012). A qualidade de vida não se alterou significativamente de acordo com o tempo de pós-operatório e distância da anastomose à margem anal. Conclui-se que os pacientes submetidos à ETM apresentam uma boa qualidade de vida após um ano de cirurgia e que os fatores envolvidos capazes de influenciar a QV devem ser identifica- dos e otimizados. Keywords: Quality of life, Rectal neoplasms, Colorectal surgery, Postoperative evaluation, Palavras-chave: Qualidade de vida, Neoplasias retais, Cirurgia colorretal, Pós-operatóriohttp://www.sciencedirect.com/science/article/pii/S2237936313000208 |
| spellingShingle | Paulo Rocha França Neto Fábio Lopes de Queiroz Isabella Rocha França Longo Staino Antônio Lacerda Filho Quality of life assessment in the late postoperative period of patients with rectal cancer submitted to total mesorectal excision Journal of Coloproctology |
| title | Quality of life assessment in the late postoperative period of patients with rectal cancer submitted to total mesorectal excision |
| title_full | Quality of life assessment in the late postoperative period of patients with rectal cancer submitted to total mesorectal excision |
| title_fullStr | Quality of life assessment in the late postoperative period of patients with rectal cancer submitted to total mesorectal excision |
| title_full_unstemmed | Quality of life assessment in the late postoperative period of patients with rectal cancer submitted to total mesorectal excision |
| title_short | Quality of life assessment in the late postoperative period of patients with rectal cancer submitted to total mesorectal excision |
| title_sort | quality of life assessment in the late postoperative period of patients with rectal cancer submitted to total mesorectal excision |
| url | http://www.sciencedirect.com/science/article/pii/S2237936313000208 |
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