Coinfection with influenza virus and non-typeable Haemophilus influenzae aggregates inflammatory lung injury and alters gut microbiota in COPD mice

Coinfection with influenza virus and non-typeable Haemophilus influenzae aggregates inflammatory lung injury and alters gut microbiota in COPD mice

BackgroundAcute exacerbation of chronic obstructive pulmonary disease (AECOPD) is associated with high mortality rates. Viral and bacterial coinfection is the primary cause of AECOPD. How coinfection with these microbes influences host inflammatory response and the gut microbiota composition is not...

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Bibliographic Details
Main Authors: Xiao Wu, Run-Feng Li, Zheng-Shi Lin, Chuang Xiao, Bin Liu, Kai-Lin Mai, Hong-Xia Zhou, De-You Zeng, Sha Cheng, Yun-Ceng Weng, Jin Zhao, Rui-Feng Chen, Hai-Ming Jiang, Li-Ping Chen, Ling-Zhu Deng, Pei-Fang Xie, Wei-Min Yang, Xue-Shan Xia, Zi-Feng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Microbiology
Subjects:
COPD
influenza
influenzae
mice
inflammation
microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1137369/full

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