Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review
Yibeltal Aschale,1 Bantayehu Addis Tegegne,2 Wubetu Yihunie2 1Department of Medical Laboratory Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of Pharmacy, Debre Markos University, Debre Markos, EthiopiaCorrespondence: Yibeltal Aschale, Tel +251910962733, Email yibea33@gmail.c...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-03-01
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| Series: | Hepatic Medicine: Evidence and Research |
| Subjects: | |
| Online Access: | https://www.dovepress.com/medicinal-plants-used-for-the-management-of-hepatitis-over-the-past-15-peer-reviewed-fulltext-article-HMER |
| _version_ | 1811155600884629504 |
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| author | Aschale Y Tegegne BA Yihunie W |
| author_facet | Aschale Y Tegegne BA Yihunie W |
| author_sort | Aschale Y |
| collection | DOAJ |
| description | Yibeltal Aschale,1 Bantayehu Addis Tegegne,2 Wubetu Yihunie2 1Department of Medical Laboratory Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of Pharmacy, Debre Markos University, Debre Markos, EthiopiaCorrespondence: Yibeltal Aschale, Tel +251910962733, Email yibea33@gmail.comBackground: Treatment of human and animal ailments using botanical sources has obtained significant attention in Ethiopia. The compounds available in plants comprise a plentiful source of bioactive ingredients able to treat many complications. The review aimed to present an updated list of plants used for managing hepatitis over the past 15 years in Ethiopia.Methods: Systematic, comprehensive search was undertaken from electronic databases (PubMed, Google Scholar, Science Direct, and Scopus) between September 01 and October 15, 2022, using standard search terms. Original researches carried out in Ethiopia, written and published in English between January 01/2007 and December 31/2021, and reported hepatitis as a disease treated by medicinal plants were included in the review. Plants beyond the list of Ethiopian and Eritrean floral were excluded. Data were extracted from texts and tables of original papers on a Microsoft Excel. Quality was assessed by applying the Joanna Briggs Institute Critical Appraisal Checklist.Results: A total of 317 papers were obtained from the database search. After removing duplicates and screening, 15 articles fit the inclusion criteria and selected for final review. Of the 24 plants identified, 35.7% were herbs. Leaf and root (35.7% each) were the predominant plant parts used for remedy preparation. Combined use of leaf and root comprised 10.7%. The families Apocynaceae, Asteraceae, Euphorbiaceae, Cucurbitaceae, and Fabaceae comprise the highest number of plant species. About 89.3% of remedies were administered orally.Conclusion: The majority of plants belong to herbs and the frequently used plant parts are leaf and roots. Evidence generated from the present review indicated that lots of plants have been used to manage hepatitis. Moreover, the findings could serve as preliminary information to formulate new drugs acting against hepatitis. Therefore, it is desirable for scholars to recognize, document, and keep plants and the associated knowledge appropriately.Keywords: hepatitis, medicinal plant, Ethiopia |
| first_indexed | 2024-04-10T04:37:16Z |
| format | Article |
| id | doaj.art-44fb9c6725744d5796a1e75cfd7b4ef5 |
| institution | Directory Open Access Journal |
| issn | 1179-1535 |
| language | English |
| last_indexed | 2024-04-10T04:37:16Z |
| publishDate | 2023-03-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Hepatic Medicine: Evidence and Research |
| spelling | doaj.art-44fb9c6725744d5796a1e75cfd7b4ef52023-03-09T16:47:04ZengDove Medical PressHepatic Medicine: Evidence and Research1179-15352023-03-01Volume 15111982140Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic ReviewAschale YTegegne BAYihunie WYibeltal Aschale,1 Bantayehu Addis Tegegne,2 Wubetu Yihunie2 1Department of Medical Laboratory Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of Pharmacy, Debre Markos University, Debre Markos, EthiopiaCorrespondence: Yibeltal Aschale, Tel +251910962733, Email yibea33@gmail.comBackground: Treatment of human and animal ailments using botanical sources has obtained significant attention in Ethiopia. The compounds available in plants comprise a plentiful source of bioactive ingredients able to treat many complications. The review aimed to present an updated list of plants used for managing hepatitis over the past 15 years in Ethiopia.Methods: Systematic, comprehensive search was undertaken from electronic databases (PubMed, Google Scholar, Science Direct, and Scopus) between September 01 and October 15, 2022, using standard search terms. Original researches carried out in Ethiopia, written and published in English between January 01/2007 and December 31/2021, and reported hepatitis as a disease treated by medicinal plants were included in the review. Plants beyond the list of Ethiopian and Eritrean floral were excluded. Data were extracted from texts and tables of original papers on a Microsoft Excel. Quality was assessed by applying the Joanna Briggs Institute Critical Appraisal Checklist.Results: A total of 317 papers were obtained from the database search. After removing duplicates and screening, 15 articles fit the inclusion criteria and selected for final review. Of the 24 plants identified, 35.7% were herbs. Leaf and root (35.7% each) were the predominant plant parts used for remedy preparation. Combined use of leaf and root comprised 10.7%. The families Apocynaceae, Asteraceae, Euphorbiaceae, Cucurbitaceae, and Fabaceae comprise the highest number of plant species. About 89.3% of remedies were administered orally.Conclusion: The majority of plants belong to herbs and the frequently used plant parts are leaf and roots. Evidence generated from the present review indicated that lots of plants have been used to manage hepatitis. Moreover, the findings could serve as preliminary information to formulate new drugs acting against hepatitis. Therefore, it is desirable for scholars to recognize, document, and keep plants and the associated knowledge appropriately.Keywords: hepatitis, medicinal plant, Ethiopiahttps://www.dovepress.com/medicinal-plants-used-for-the-management-of-hepatitis-over-the-past-15-peer-reviewed-fulltext-article-HMERhepatitismedicinal plantethiopia |
| spellingShingle | Aschale Y Tegegne BA Yihunie W Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review Hepatic Medicine: Evidence and Research hepatitis medicinal plant ethiopia |
| title | Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review |
| title_full | Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review |
| title_fullStr | Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review |
| title_full_unstemmed | Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review |
| title_short | Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review |
| title_sort | medicinal plants used for the management of hepatitis over the past 15 years in ethiopia a systematic review |
| topic | hepatitis medicinal plant ethiopia |
| url | https://www.dovepress.com/medicinal-plants-used-for-the-management-of-hepatitis-over-the-past-15-peer-reviewed-fulltext-article-HMER |
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