New Chemical Probe Targeting Bacterial NAD Kinase

New Chemical Probe Targeting Bacterial NAD Kinase

Nicotinamide adenine dinucleotide (NAD) kinases are essential and ubiquitous enzymes involved in the tight regulation of NAD/nicotinamide adenine dinucleotide phosphate (NADP) levels in many metabolic pathways. Consequently, they represent promising therapeutic targets in cancer and antibacterial tr...

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Bibliographic Details
Main Authors:	David A. Clément, Clarisse Leseigneur, Muriel Gelin, Dylan Coelho, Valérie Huteau, Corinne Lionne, Gilles Labesse, Olivier Dussurget, Sylvie Pochet
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Series:	Molecules
Subjects:	antibiotics chemical probe diadenosine derivatives NAD kinase nucleoside Sonogashira coupling
Online Access:	https://www.mdpi.com/1420-3049/25/21/4893

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