The potential effects and mechanisms of Gegen Qinlian Decoction in oxaliplatin-resistant colorectal cancer based on network pharmacology

The potential effects and mechanisms of Gegen Qinlian Decoction in oxaliplatin-resistant colorectal cancer based on network pharmacology

Background: Resistance to chemotherapeutic drugs, such as oxaliplatin (OXA), can lead to unsatisfactory chemotherapy results during the treatment of advanced colorectal cancer (CRC). Therefore, we investigated the potential targets and mechanisms of Gegen Qinlian Decoction (GQD) against OXA-resistan...

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Bibliographic Details
Main Authors:	Xiang Lin, Li Xu, Huicheng Tan, Xinyi Zhang, Huan Shao, Li Yao, Xuan Huang
Format:	Article
Language:	English
Published:	Elsevier 2022-11-01
Series:	Heliyon
Subjects:	Colorectal cancer Gegen qinlian decoction Chemotherapy resistance Network pharmacology ABC transporter
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844022025932

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