Prevalence of Carbapenem-Resistant Enterobacterales, Acinetobacter baumannii, and Pseudomonas aeruginosa in a Tertiary Care Hospital in Eastern India: A Pilot Study
In recent years, a wide range of clinical infections are being caused by carbapenem-resistant Enterobacterales, Acinetobacter baumannii and Pseudomonas aeruginosa. This is a matter of great concern, as carbapenem-resistant infections have fewer treatment options. The Enterobacterales comprises a lar...
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| Format: | Article |
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Journal of Pure and Applied Microbiology
2023-12-01
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| Series: | Journal of Pure and Applied Microbiology |
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| Online Access: | https://microbiologyjournal.org/prevalence-of-carbapenem-resistant-enterobacterales-acinetobacter-baumannii-and-pseudomonas-aeruginosa-in-a-tertiary-care-hospital-in-eastern-india-a-pilot-study/ |
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| author | Gaurav Verma Subham Ravi Nayak Swetapadma Jena Subhra Snigdha Panda Dipti Pattnaik A.K. Praharaj Nipa Singh |
| author_facet | Gaurav Verma Subham Ravi Nayak Swetapadma Jena Subhra Snigdha Panda Dipti Pattnaik A.K. Praharaj Nipa Singh |
| author_sort | Gaurav Verma |
| collection | DOAJ |
| description | In recent years, a wide range of clinical infections are being caused by carbapenem-resistant Enterobacterales, Acinetobacter baumannii and Pseudomonas aeruginosa. This is a matter of great concern, as carbapenem-resistant infections have fewer treatment options. The Enterobacterales comprises a large group of bacterial species commonly causing infections in healthcare settings. The most common bacteria are Escherichia coli and Klebsiella pneumoniae, which can cause both nosocomial and community-acquired infections. This study aimed to determine the prevalence of carbapenem-resistant Enterobacterales, P. aeruginosa, and A. baumannii, in a tertiary care center in India. The study was conducted over a period of seven months, from May 2022 to November 2022. The specimens were processed at the Microbiology Laboratory of Kalinga Institute of Medical Sciences- Pradyumna Bal Memorial Hospital, Bhubaneswar. Standard procedures were used to process the clinical specimens brought to the laboratory. Carbapenem-resistant isolates were screened according to the CLSI 2022 guidelines. This study included 3,006 isolates of Enterobacterales, A. baumannii, and P. aeruginosa. Of these, 29.40% (n = 844) were found to be carbapenem resistant. The breakup is as follows: 689 (77.94%) were Enterobacterales, 108 (12.21%) were A. baumannii, and 87 (9.84%) were P. aeruginosa. Thus, our investigation revealed an overall prevalence of carbapenem-resistant Enterobacterales, A. baumannii, and P. aeruginosa of 29.40%, which corresponds to previous studies in India. Early patient screening, isolation, and contact prevention measures will help reduce infection transmission. Further, larger multi-centric studies are required to obtain a wider perspective regarding this issue. |
| first_indexed | 2024-03-08T22:51:26Z |
| format | Article |
| id | doaj.art-45006192da934c7c88f3b4709156da0b |
| institution | Directory Open Access Journal |
| issn | 0973-7510 2581-690X |
| language | English |
| last_indexed | 2024-03-08T22:51:26Z |
| publishDate | 2023-12-01 |
| publisher | Journal of Pure and Applied Microbiology |
| record_format | Article |
| series | Journal of Pure and Applied Microbiology |
| spelling | doaj.art-45006192da934c7c88f3b4709156da0b2023-12-16T11:06:23ZengJournal of Pure and Applied MicrobiologyJournal of Pure and Applied Microbiology0973-75102581-690X2023-12-0117422432249https://doi.org/10.22207/JPAM.17.4.21Prevalence of Carbapenem-Resistant Enterobacterales, Acinetobacter baumannii, and Pseudomonas aeruginosa in a Tertiary Care Hospital in Eastern India: A Pilot StudyGaurav Vermahttps://orcid.org/0000-0001-9792-8777Subham Ravi Nayakhttps://orcid.org/0000-0003-3939-891XSwetapadma JenaSubhra Snigdha Pandahttps://orcid.org/0000-0003-4804-3598Dipti Pattnaikhttps://orcid.org/0000-0002-6427-1841A.K. PraharajNipa Singhhttps://orcid.org/0000-0001-8800-2892In recent years, a wide range of clinical infections are being caused by carbapenem-resistant Enterobacterales, Acinetobacter baumannii and Pseudomonas aeruginosa. This is a matter of great concern, as carbapenem-resistant infections have fewer treatment options. The Enterobacterales comprises a large group of bacterial species commonly causing infections in healthcare settings. The most common bacteria are Escherichia coli and Klebsiella pneumoniae, which can cause both nosocomial and community-acquired infections. This study aimed to determine the prevalence of carbapenem-resistant Enterobacterales, P. aeruginosa, and A. baumannii, in a tertiary care center in India. The study was conducted over a period of seven months, from May 2022 to November 2022. The specimens were processed at the Microbiology Laboratory of Kalinga Institute of Medical Sciences- Pradyumna Bal Memorial Hospital, Bhubaneswar. Standard procedures were used to process the clinical specimens brought to the laboratory. Carbapenem-resistant isolates were screened according to the CLSI 2022 guidelines. This study included 3,006 isolates of Enterobacterales, A. baumannii, and P. aeruginosa. Of these, 29.40% (n = 844) were found to be carbapenem resistant. The breakup is as follows: 689 (77.94%) were Enterobacterales, 108 (12.21%) were A. baumannii, and 87 (9.84%) were P. aeruginosa. Thus, our investigation revealed an overall prevalence of carbapenem-resistant Enterobacterales, A. baumannii, and P. aeruginosa of 29.40%, which corresponds to previous studies in India. Early patient screening, isolation, and contact prevention measures will help reduce infection transmission. Further, larger multi-centric studies are required to obtain a wider perspective regarding this issue.https://microbiologyjournal.org/prevalence-of-carbapenem-resistant-enterobacterales-acinetobacter-baumannii-and-pseudomonas-aeruginosa-in-a-tertiary-care-hospital-in-eastern-india-a-pilot-study/carbapenem resistantenterobacteralespseudomonas aeruginosaacinetobacter baumannii |
| spellingShingle | Gaurav Verma Subham Ravi Nayak Swetapadma Jena Subhra Snigdha Panda Dipti Pattnaik A.K. Praharaj Nipa Singh Prevalence of Carbapenem-Resistant Enterobacterales, Acinetobacter baumannii, and Pseudomonas aeruginosa in a Tertiary Care Hospital in Eastern India: A Pilot Study Journal of Pure and Applied Microbiology carbapenem resistant enterobacterales pseudomonas aeruginosa acinetobacter baumannii |
| title | Prevalence of Carbapenem-Resistant Enterobacterales, Acinetobacter baumannii, and Pseudomonas aeruginosa in a Tertiary Care Hospital in Eastern India: A Pilot Study |
| title_full | Prevalence of Carbapenem-Resistant Enterobacterales, Acinetobacter baumannii, and Pseudomonas aeruginosa in a Tertiary Care Hospital in Eastern India: A Pilot Study |
| title_fullStr | Prevalence of Carbapenem-Resistant Enterobacterales, Acinetobacter baumannii, and Pseudomonas aeruginosa in a Tertiary Care Hospital in Eastern India: A Pilot Study |
| title_full_unstemmed | Prevalence of Carbapenem-Resistant Enterobacterales, Acinetobacter baumannii, and Pseudomonas aeruginosa in a Tertiary Care Hospital in Eastern India: A Pilot Study |
| title_short | Prevalence of Carbapenem-Resistant Enterobacterales, Acinetobacter baumannii, and Pseudomonas aeruginosa in a Tertiary Care Hospital in Eastern India: A Pilot Study |
| title_sort | prevalence of carbapenem resistant enterobacterales acinetobacter baumannii and pseudomonas aeruginosa in a tertiary care hospital in eastern india a pilot study |
| topic | carbapenem resistant enterobacterales pseudomonas aeruginosa acinetobacter baumannii |
| url | https://microbiologyjournal.org/prevalence-of-carbapenem-resistant-enterobacterales-acinetobacter-baumannii-and-pseudomonas-aeruginosa-in-a-tertiary-care-hospital-in-eastern-india-a-pilot-study/ |
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