A revised risk analysis of stress ulcers in burn patients receiving ulcer prophylaxis
Objective Most of the literature about Curling’s ulcer was published from 1960 through 1980. Therefore, an updated study of Curling’s ulcer is needed. We analyzed the risk factors affecting ulcer incidence in burn patients. Methods We retrospectively analyzed the medical records of burn patients who...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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The Korean Society of Emergency Medicine
2015-12-01
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| Series: | Clinical and Experimental Emergency Medicine |
| Subjects: | |
| Online Access: | http://www.ceemjournal.org/upload/pdf/ceem-15-076.pdf |
| _version_ | 1797897217263009792 |
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| author | Young Hwan Choi Jong Ho Lee Jae Jun Shin Young Soon Cho |
| author_facet | Young Hwan Choi Jong Ho Lee Jae Jun Shin Young Soon Cho |
| author_sort | Young Hwan Choi |
| collection | DOAJ |
| description | Objective Most of the literature about Curling’s ulcer was published from 1960 through 1980. Therefore, an updated study of Curling’s ulcer is needed. We analyzed the risk factors affecting ulcer incidence in burn patients. Methods We retrospectively analyzed the medical records of burn patients who were admitted to two burn centers. We collected information about the general characteristics of patients, burn area size, abbreviated burn severity index, whether surgery was performed, endoscopy results, and the total body surface area (TBSA). We performed a multivariate regression analysis predicting development of Curling’s ulcer. Results In total, 135 patients (mean age, 49.5±13.5 years) underwent endoscopy. Endoscopy revealed ulcer in 51 patients: 36 (70.6%) with gastric ulcers, 9 (17.6%) with duodenal ulcers, and 6 (11.8%) with both ulcer types. Burn area, burn depth, epigastric pain, melena, intensive care unit admission, burn area >20% of TBSA, and undergoing surgery for the burn were significantly different between the ulcer and non-ulcer groups. Multivariate analysis showed two independent factors significantly associated with ulcer: epigastric pain (odds ratio [OR]: 4.55, 95% confidence interval [CI]: 1.74 to 11.90), major burn (TBSA > 20%)(OR: 4.31 ,95% CI: 1.34 to 13.85). Conclusion For burn patients, presence of epigastric pain and major burn with TBSA > 20% showed significant association with ulcer development. |
| first_indexed | 2024-04-10T07:54:04Z |
| format | Article |
| id | doaj.art-45046f65512140399bb7b3c5fbddf6c3 |
| institution | Directory Open Access Journal |
| issn | 2383-4625 |
| language | English |
| last_indexed | 2024-04-10T07:54:04Z |
| publishDate | 2015-12-01 |
| publisher | The Korean Society of Emergency Medicine |
| record_format | Article |
| series | Clinical and Experimental Emergency Medicine |
| spelling | doaj.art-45046f65512140399bb7b3c5fbddf6c32023-02-23T05:33:26ZengThe Korean Society of Emergency MedicineClinical and Experimental Emergency Medicine2383-46252015-12-012425025510.15441/ceem.15.07666A revised risk analysis of stress ulcers in burn patients receiving ulcer prophylaxisYoung Hwan Choi0Jong Ho Lee1Jae Jun Shin2Young Soon Cho3 Department of Emergency Medicine, Bestian Hospital, Seoul, Korea Department of Emergency Medicine, Bestian Hospital, Seoul, Korea Department of General Surgery, Bestian Hospital, Seoul, Korea Department of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, KoreaObjective Most of the literature about Curling’s ulcer was published from 1960 through 1980. Therefore, an updated study of Curling’s ulcer is needed. We analyzed the risk factors affecting ulcer incidence in burn patients. Methods We retrospectively analyzed the medical records of burn patients who were admitted to two burn centers. We collected information about the general characteristics of patients, burn area size, abbreviated burn severity index, whether surgery was performed, endoscopy results, and the total body surface area (TBSA). We performed a multivariate regression analysis predicting development of Curling’s ulcer. Results In total, 135 patients (mean age, 49.5±13.5 years) underwent endoscopy. Endoscopy revealed ulcer in 51 patients: 36 (70.6%) with gastric ulcers, 9 (17.6%) with duodenal ulcers, and 6 (11.8%) with both ulcer types. Burn area, burn depth, epigastric pain, melena, intensive care unit admission, burn area >20% of TBSA, and undergoing surgery for the burn were significantly different between the ulcer and non-ulcer groups. Multivariate analysis showed two independent factors significantly associated with ulcer: epigastric pain (odds ratio [OR]: 4.55, 95% confidence interval [CI]: 1.74 to 11.90), major burn (TBSA > 20%)(OR: 4.31 ,95% CI: 1.34 to 13.85). Conclusion For burn patients, presence of epigastric pain and major burn with TBSA > 20% showed significant association with ulcer development.http://www.ceemjournal.org/upload/pdf/ceem-15-076.pdfburnsstomach ulcerduodenal ulcer |
| spellingShingle | Young Hwan Choi Jong Ho Lee Jae Jun Shin Young Soon Cho A revised risk analysis of stress ulcers in burn patients receiving ulcer prophylaxis Clinical and Experimental Emergency Medicine burns stomach ulcer duodenal ulcer |
| title | A revised risk analysis of stress ulcers in burn patients receiving ulcer prophylaxis |
| title_full | A revised risk analysis of stress ulcers in burn patients receiving ulcer prophylaxis |
| title_fullStr | A revised risk analysis of stress ulcers in burn patients receiving ulcer prophylaxis |
| title_full_unstemmed | A revised risk analysis of stress ulcers in burn patients receiving ulcer prophylaxis |
| title_short | A revised risk analysis of stress ulcers in burn patients receiving ulcer prophylaxis |
| title_sort | revised risk analysis of stress ulcers in burn patients receiving ulcer prophylaxis |
| topic | burns stomach ulcer duodenal ulcer |
| url | http://www.ceemjournal.org/upload/pdf/ceem-15-076.pdf |
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