In situ effect of CPP-ACP chewing gum upon erosive enamel loss
Abstract Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) is able to increase salivary calcium and phosphate levels at an acidic pH. Previous studies demonstrated that a CPP-ACP chewing gum was able to enhance the re-hardening of erosion lesions, but could not diminish enamel hardness los...
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| Format: | Article |
| Language: | English |
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University of São Paulo
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| Series: | Journal of Applied Oral Science |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000300258&lng=en&tlng=en |
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| author | Catarina Ribeiro Barros de ALENCAR Gabriela Cristina de OLIVEIRA Ana Carolina MAGALHÃES Marília Afonso Rabelo BUZALAF Maria Aparecida de Andrade Moreira MACHADO Heitor Marques HONÓRIO Daniela RIOS |
| author_facet | Catarina Ribeiro Barros de ALENCAR Gabriela Cristina de OLIVEIRA Ana Carolina MAGALHÃES Marília Afonso Rabelo BUZALAF Maria Aparecida de Andrade Moreira MACHADO Heitor Marques HONÓRIO Daniela RIOS |
| author_sort | Catarina Ribeiro Barros de ALENCAR |
| collection | DOAJ |
| description | Abstract Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) is able to increase salivary calcium and phosphate levels at an acidic pH. Previous studies demonstrated that a CPP-ACP chewing gum was able to enhance the re-hardening of erosion lesions, but could not diminish enamel hardness loss. Therefore, there is no consensus regarding the effectiveness of CPP-ACP on dental erosion. Objective This in situ study investigated the ability of a CPP-ACP chewing gum in preventing erosive enamel loss. Material and Methods: During three experimental crossover phases (one phase per group) of seven days each, eight volunteers wore palatal devices with human enamel blocks. The groups were: GI – Sugar free chewing gum with CPP-ACP; GII – Conventional sugar free chewing gum; and GIII – No chewing gum (control). Erosive challenge was extraorally performed by immersion of the enamel blocks in cola drink (5 min, 4x/day). After each challenge, in groups CPP and No CPP, volunteers chewed one unit of the corresponding chewing gum for 30 minutes. Quantitative analysis of enamel loss was performed by profilometry (µm). Data were analyzed by Repeated-Measures ANOVA and Tukey’s test (p<0.05). Results The use of chewing gum (CPP and No CPP) resulted in lower erosive enamel loss compared with the control group (p<0.05). CPP-ACP chewing gum (CPP) did not improve the protection against erosive enamel loss compared with conventional chewing gum (No CPP) (p>0.05). Conclusion The CPP-ACP chewing gum was not able to enhance the anti-erosive effect of conventional chewing gum against enamel loss. |
| first_indexed | 2024-12-21T13:08:48Z |
| format | Article |
| id | doaj.art-450561f3cb37427883115a785fd41b98 |
| institution | Directory Open Access Journal |
| issn | 1678-7765 |
| language | English |
| last_indexed | 2024-12-21T13:08:48Z |
| publisher | University of São Paulo |
| record_format | Article |
| series | Journal of Applied Oral Science |
| spelling | doaj.art-450561f3cb37427883115a785fd41b982022-12-21T19:02:57ZengUniversity of São PauloJournal of Applied Oral Science1678-776525325826410.1590/1678-7757-2016-0304S1678-77572017000300258In situ effect of CPP-ACP chewing gum upon erosive enamel lossCatarina Ribeiro Barros de ALENCARGabriela Cristina de OLIVEIRAAna Carolina MAGALHÃESMarília Afonso Rabelo BUZALAFMaria Aparecida de Andrade Moreira MACHADOHeitor Marques HONÓRIODaniela RIOSAbstract Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) is able to increase salivary calcium and phosphate levels at an acidic pH. Previous studies demonstrated that a CPP-ACP chewing gum was able to enhance the re-hardening of erosion lesions, but could not diminish enamel hardness loss. Therefore, there is no consensus regarding the effectiveness of CPP-ACP on dental erosion. Objective This in situ study investigated the ability of a CPP-ACP chewing gum in preventing erosive enamel loss. Material and Methods: During three experimental crossover phases (one phase per group) of seven days each, eight volunteers wore palatal devices with human enamel blocks. The groups were: GI – Sugar free chewing gum with CPP-ACP; GII – Conventional sugar free chewing gum; and GIII – No chewing gum (control). Erosive challenge was extraorally performed by immersion of the enamel blocks in cola drink (5 min, 4x/day). After each challenge, in groups CPP and No CPP, volunteers chewed one unit of the corresponding chewing gum for 30 minutes. Quantitative analysis of enamel loss was performed by profilometry (µm). Data were analyzed by Repeated-Measures ANOVA and Tukey’s test (p<0.05). Results The use of chewing gum (CPP and No CPP) resulted in lower erosive enamel loss compared with the control group (p<0.05). CPP-ACP chewing gum (CPP) did not improve the protection against erosive enamel loss compared with conventional chewing gum (No CPP) (p>0.05). Conclusion The CPP-ACP chewing gum was not able to enhance the anti-erosive effect of conventional chewing gum against enamel loss.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000300258&lng=en&tlng=enTooth erosionDental enamelTooth wearChewing gumCasein phosphopeptide-amorphous calcium phosphate |
| spellingShingle | Catarina Ribeiro Barros de ALENCAR Gabriela Cristina de OLIVEIRA Ana Carolina MAGALHÃES Marília Afonso Rabelo BUZALAF Maria Aparecida de Andrade Moreira MACHADO Heitor Marques HONÓRIO Daniela RIOS In situ effect of CPP-ACP chewing gum upon erosive enamel loss Journal of Applied Oral Science Tooth erosion Dental enamel Tooth wear Chewing gum Casein phosphopeptide-amorphous calcium phosphate |
| title | In situ effect of CPP-ACP chewing gum upon erosive enamel loss |
| title_full | In situ effect of CPP-ACP chewing gum upon erosive enamel loss |
| title_fullStr | In situ effect of CPP-ACP chewing gum upon erosive enamel loss |
| title_full_unstemmed | In situ effect of CPP-ACP chewing gum upon erosive enamel loss |
| title_short | In situ effect of CPP-ACP chewing gum upon erosive enamel loss |
| title_sort | in situ effect of cpp acp chewing gum upon erosive enamel loss |
| topic | Tooth erosion Dental enamel Tooth wear Chewing gum Casein phosphopeptide-amorphous calcium phosphate |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000300258&lng=en&tlng=en |
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