Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery
Background: Increased serum lactate during cardio-pulmonary bypass is associated with high mortality and cardiac complications up to 10-20 percent. The aim of this study was to evaluate the effect of serum lactate increase on postoperative outcomes after coronary artery bypass graft (CABG) Surgery....
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| Format: | Article |
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Kashan University of Medical Sciences and Health Services
2017-02-01
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| Series: | Fiyz̤ |
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| Online Access: | http://feyz.kaums.ac.ir/article-1-3225-en.html |
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| author | Fatemeh Hasanshiri Mohammad Sadegh Pourabbasi Seyyed Gholam Abbas Mousavi Mojdeh Fatahi Amir Abbas Kianfar Hamid Reza Seyedi Fakhrosadat Mirhoseini Mehrdad Mahdian |
| author_facet | Fatemeh Hasanshiri Mohammad Sadegh Pourabbasi Seyyed Gholam Abbas Mousavi Mojdeh Fatahi Amir Abbas Kianfar Hamid Reza Seyedi Fakhrosadat Mirhoseini Mehrdad Mahdian |
| author_sort | Fatemeh Hasanshiri |
| collection | DOAJ |
| description | Background: Increased serum lactate during cardio-pulmonary bypass is associated with high mortality and cardiac complications up to 10-20 percent. The aim of this study was to evaluate the effect of serum lactate increase on postoperative outcomes after coronary artery bypass graft (CABG) Surgery.
Materials and Methods: This descriptive-analytical study was performed on cases (no=116) undergoing CABG at Beheshti hospital in Kashan between 2013-2014. Demographic data, variables related to surgery, serum lactate level and the time of tracheal extubation, length of stay in intensive care unit (ICU) and hospital post-surgery left ventricular ejection fraction were collected. These data was compared in two groups: Normal serum lactate (< 2 m mol\liter) and Hyperlactatemia (> 2 m mol\liter) group.
Results: The postoperative hyperlactatemia was observed in 62.1 % of patients. There were no significant differences between two groups in time of tracheal extubation, length of stay in ICU and hospital. There was a relationship between the mean postoperative serum lactate and blood sugar, bicarbonate, pH, length of cardiopulmonary bypass and the aortic cross clamping time. There was a significant relationship between the serum lactate increment and the left ventricular ejection fraction decrement.
Conclusion: Hyperlactatemia is probably associated with such important factors as high blood sugar, longer duration of aortic cross clamp and cardio-pulmonary bypass time. So controlling such factors can reduce the rate of hyperlactatemia and help postoperative recovery. |
| first_indexed | 2024-12-16T07:08:50Z |
| format | Article |
| id | doaj.art-45061d74509e4185b9a5f820e02b8e43 |
| institution | Directory Open Access Journal |
| issn | 1029-7855 2008-9821 |
| language | fas |
| last_indexed | 2024-12-16T07:08:50Z |
| publishDate | 2017-02-01 |
| publisher | Kashan University of Medical Sciences and Health Services |
| record_format | Article |
| series | Fiyz̤ |
| spelling | doaj.art-45061d74509e4185b9a5f820e02b8e432022-12-21T22:39:57ZfasKashan University of Medical Sciences and Health ServicesFiyz̤1029-78552008-98212017-02-01206518524Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgeryFatemeh Hasanshiri 0Mohammad Sadegh Pourabbasi 1Seyyed Gholam Abbas Mousavi 2Mojdeh Fatahi3Amir Abbas Kianfar4Hamid Reza Seyedi5Fakhrosadat Mirhoseini 6 Mehrdad Mahdian 7Shahid-Beheshti Hospital, Kashan University of Medical Sciences, Kashan, I. R. Iran.Department of Heart, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, I. R. Iran.Trauma Research Center, Kashan University of Medical Sciences, Kashan, I. R. Iran.Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, I. R. Iran.Anesthesiologist, Fellowship of Cardiac Anesthesia, Center of Children, Tehran University of Medical Sciences, Tehran, I. R. Iran.Department of Anesthesiology, Faculty of Para Medicine, Kashan University of Medical Sciences, Kashan, I. R. Iran.Department of Anesthesiology, Faculty of Para Medicine, Kashan University of Medical Sciences, Kashan, I. R. Iran.Trauma Research Center, Kashan University of Medical Sciences, Kashan, I. R. Iran.Background: Increased serum lactate during cardio-pulmonary bypass is associated with high mortality and cardiac complications up to 10-20 percent. The aim of this study was to evaluate the effect of serum lactate increase on postoperative outcomes after coronary artery bypass graft (CABG) Surgery. Materials and Methods: This descriptive-analytical study was performed on cases (no=116) undergoing CABG at Beheshti hospital in Kashan between 2013-2014. Demographic data, variables related to surgery, serum lactate level and the time of tracheal extubation, length of stay in intensive care unit (ICU) and hospital post-surgery left ventricular ejection fraction were collected. These data was compared in two groups: Normal serum lactate (< 2 m mol\liter) and Hyperlactatemia (> 2 m mol\liter) group. Results: The postoperative hyperlactatemia was observed in 62.1 % of patients. There were no significant differences between two groups in time of tracheal extubation, length of stay in ICU and hospital. There was a relationship between the mean postoperative serum lactate and blood sugar, bicarbonate, pH, length of cardiopulmonary bypass and the aortic cross clamping time. There was a significant relationship between the serum lactate increment and the left ventricular ejection fraction decrement. Conclusion: Hyperlactatemia is probably associated with such important factors as high blood sugar, longer duration of aortic cross clamp and cardio-pulmonary bypass time. So controlling such factors can reduce the rate of hyperlactatemia and help postoperative recovery.http://feyz.kaums.ac.ir/article-1-3225-en.htmlCoronary artery bypasses graftSerum lactateCardiopulmonary bypassPostoperative outcomes |
| spellingShingle | Fatemeh Hasanshiri Mohammad Sadegh Pourabbasi Seyyed Gholam Abbas Mousavi Mojdeh Fatahi Amir Abbas Kianfar Hamid Reza Seyedi Fakhrosadat Mirhoseini Mehrdad Mahdian Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery Fiyz̤ Coronary artery bypasses graft Serum lactate Cardiopulmonary bypass Postoperative outcomes |
| title | Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery |
| title_full | Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery |
| title_fullStr | Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery |
| title_full_unstemmed | Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery |
| title_short | Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery |
| title_sort | association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery |
| topic | Coronary artery bypasses graft Serum lactate Cardiopulmonary bypass Postoperative outcomes |
| url | http://feyz.kaums.ac.ir/article-1-3225-en.html |
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