Endothelial cell-type-specific molecular requirements for angiogenesis drive fenestrated vessel development in the brain
Vascular endothelial cells (vECs) in the brain exhibit structural and functional heterogeneity. Fenestrated, permeable brain vasculature mediates neuroendocrine function, body-fluid regulation, and neural immune responses; however, its vascular formation remains poorly understood. Here, we show that...
Main Authors: | Sweta Parab, Rachael E Quick, Ryota L Matsuoka |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/64295 |
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