The Application of Emodin Treatment on Nasopharyngeal Carcinoma Therapy

Nasopharyngeal carcinoma (NPC) is a malignancy prevailing in Taiwan, Hong Kong, Southern China, Southeast Asia, and North Africa. Although early-stage NPC responds well to the primary treatment of radio-chemotherapy, the mortality rate of advanced NPC remains high. Therefore, developing new therapie...

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Bibliographic Details
Main Authors: Chung-Chun Wu, Mei-Shu Chen, Jen-Yang Chen
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/12/3/486
Description
Summary:Nasopharyngeal carcinoma (NPC) is a malignancy prevailing in Taiwan, Hong Kong, Southern China, Southeast Asia, and North Africa. Although early-stage NPC responds well to the primary treatment of radio-chemotherapy, the mortality rate of advanced NPC remains high. Therefore, developing new therapies for nasopharyngeal carcinoma is an urgent task. Emodin is an anthraquinone derivative mainly found in <i>Rheum palmatum</i>. Emodin has been found to possess many anti-cancer functions against various types of cancers, but they are less discussed in the treatment of NPC. This review organized the different studies about the anti-NPC activity of emodin and discussed the potential and challenges of emodin treatment in NPC therapy.
ISSN:2227-9059