Accurate Prediction of Protein Structural Flexibility by Deep Learning Integrating Intricate Atomic Structures and Cryo-EM Density Information

Abstract The dynamics of proteins are crucial for understanding their mechanisms. However, computationally predicting protein dynamic information has proven challenging. Here, we propose a neural network model, RMSF-net, which outperforms previous methods and produces the best results in a large-sca...

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Bibliografski detalji
Glavni autori: Xintao Song, Lei Bao, Chenjie Feng, Qiang Huang, Fa Zhang, Xin Gao, Renmin Han
Format: Članak
Jezik:English
Izdano: Nature Portfolio 2024-07-01
Serija:Nature Communications
Online pristup:https://doi.org/10.1038/s41467-024-49858-x