Reserarch on the Formulation Process of Malt Chewable Tablets and Its Digestion Promoting Function
Study on the formulation process of malt chewable tablets and its digestion promoting function.Using a method combining orthogonal experiment and fuzzy comprehensive evaluation to study the formulation process of malt chewable tablets; using small intestine ink advance rate of mice， pepsin excretion...
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| Format: | Article |
| Language: | English |
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Academy of National Food and Strategic Reserves Administration
2021-01-01
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| Series: | Liang you shipin ke-ji |
| Subjects: | |
| Online Access: | http://lyspkj.ijournal.cn/lyspkj/article/abstract/20210117?st=article_issue |
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| author | GAO Ru-yi CAO Miao-miao GUO Xiao-li DENG Chen-chen HU Bao-ling LIU Wen-ying XU Ming-jun |
| author_facet | GAO Ru-yi CAO Miao-miao GUO Xiao-li DENG Chen-chen HU Bao-ling LIU Wen-ying XU Ming-jun |
| author_sort | GAO Ru-yi |
| collection | DOAJ |
| description | Study on the formulation process of malt chewable tablets and its digestion promoting function.Using a method combining orthogonal experiment and fuzzy comprehensive evaluation to study the formulation process of malt chewable tablets; using small intestine ink advance rate of mice， pepsin excretion of rats， and animal weight change as indicators to study the digestion promoting function of malt chewable tablets. The best formulas are as follows: citric acid is 2%， stevioside is 1%， microcrystalline cellulose is 40%， and magnesium stearate is 1%. 2.67 g/kg BW (body weight) of malt chewable tablets can improve the ink advancing rate of the small bowel movement experiment in mice (P＜0.001)， and the chewable tablets had no adverse effects on rat weight gain， food intake， and food utilization. Malt chewable tablets preparation process is stable and reliable， and the animal function experiments show that it has the function of promoting digestion. |
| first_indexed | 2024-03-13T06:59:57Z |
| format | Article |
| id | doaj.art-450e2b8959af41a09cdb63dd8038d431 |
| institution | Directory Open Access Journal |
| issn | 1007-7561 |
| language | English |
| last_indexed | 2024-03-13T06:59:57Z |
| publishDate | 2021-01-01 |
| publisher | Academy of National Food and Strategic Reserves Administration |
| record_format | Article |
| series | Liang you shipin ke-ji |
| spelling | doaj.art-450e2b8959af41a09cdb63dd8038d4312023-06-07T03:20:15ZengAcademy of National Food and Strategic Reserves AdministrationLiang you shipin ke-ji1007-75612021-01-0129111612110.16210/j.cnki.1007-7561.2021.01.016Reserarch on the Formulation Process of Malt Chewable Tablets and Its Digestion Promoting FunctionGAO Ru-yi0 CAO Miao-miao1GUO Xiao-li2DENG Chen-chen3HU Bao-ling4 LIU Wen-ying5 XU Ming-jun6Jiangsu Kanion Pharmaceutical Co.， Ltd.， State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical， Lianyungang， Jiangsu 222001， ChinaJiangsu Kanion Pharmaceutical Co.， Ltd.， State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical， Lianyungang， Jiangsu 222001， ChinaJiangsu Kanion Pharmaceutical Co.， Ltd.， State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical， Lianyungang， Jiangsu 222001， ChinaJiangsu Kanion Pharmaceutical Co.， Ltd.， State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical， Lianyungang， Jiangsu 222001， ChinaJiangsu Kanion Pharmaceutical Co.， Ltd.， State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical， Lianyungang， Jiangsu 222001， ChinaJiangsu Kanion Pharmaceutical Co.， Ltd.， State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical， Lianyungang， Jiangsu 222001， ChinaJiangsu Kanion Pharmaceutical Co.， Ltd.， State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical， Lianyungang， Jiangsu 222001， ChinaStudy on the formulation process of malt chewable tablets and its digestion promoting function.Using a method combining orthogonal experiment and fuzzy comprehensive evaluation to study the formulation process of malt chewable tablets; using small intestine ink advance rate of mice， pepsin excretion of rats， and animal weight change as indicators to study the digestion promoting function of malt chewable tablets. The best formulas are as follows: citric acid is 2%， stevioside is 1%， microcrystalline cellulose is 40%， and magnesium stearate is 1%. 2.67 g/kg BW (body weight) of malt chewable tablets can improve the ink advancing rate of the small bowel movement experiment in mice (P＜0.001)， and the chewable tablets had no adverse effects on rat weight gain， food intake， and food utilization. Malt chewable tablets preparation process is stable and reliable， and the animal function experiments show that it has the function of promoting digestion.http://lyspkj.ijournal.cn/lyspkj/article/abstract/20210117?st=article_issuemalt chewable tabletsformulatpreparation processdigestive functionanimal experiment |
| spellingShingle | GAO Ru-yi CAO Miao-miao GUO Xiao-li DENG Chen-chen HU Bao-ling LIU Wen-ying XU Ming-jun Reserarch on the Formulation Process of Malt Chewable Tablets and Its Digestion Promoting Function Liang you shipin ke-ji malt chewable tablets formulat preparation process digestive function animal experiment |
| title | Reserarch on the Formulation Process of Malt Chewable Tablets and Its Digestion Promoting Function |
| title_full | Reserarch on the Formulation Process of Malt Chewable Tablets and Its Digestion Promoting Function |
| title_fullStr | Reserarch on the Formulation Process of Malt Chewable Tablets and Its Digestion Promoting Function |
| title_full_unstemmed | Reserarch on the Formulation Process of Malt Chewable Tablets and Its Digestion Promoting Function |
| title_short | Reserarch on the Formulation Process of Malt Chewable Tablets and Its Digestion Promoting Function |
| title_sort | reserarch on the formulation process of malt chewable tablets and its digestion promoting function |
| topic | malt chewable tablets formulat preparation process digestive function animal experiment |
| url | http://lyspkj.ijournal.cn/lyspkj/article/abstract/20210117?st=article_issue |
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