Oncogenic Signaling in Tumorigenesis and Applications of siRNA Nanotherapeutics in Breast Cancer

Oncogenic Signaling in Tumorigenesis and Applications of siRNA Nanotherapeutics in Breast Cancer

Overexpression of oncogenes and cross-talks of the oncoproteins-regulated signaling cascades with other intracellular pathways in breast cancer could lead to massive abnormal signaling with the consequence of tumorigenesis. The ability to identify the genes having vital roles in cancer development w...

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Bibliographic Details
Main Authors: Nur Izyani Kamaruzman, Noraini Abd Aziz, Chit Laa Poh, Ezharul Hoque Chowdhury
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
breast cancer
siRNA
cell signaling
active targeting
passive targeting
EPR effect
oncogenes
nanoparticles
nanomedicine
Online Access:https://www.mdpi.com/2072-6694/11/5/632

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